KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IQGAP3
All Species:
4.24
Human Site:
T1163
Identified Species:
15.56
UniProt:
Q86VI3
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VI3
NP_839943.2
1631
184699
T1163
A
E
K
F
P
D
A
T
D
S
E
V
Y
K
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547533
1692
191049
S1224
A
E
K
F
P
D
N
S
E
N
E
V
Y
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKF1
1657
188738
G1179
H
E
K
F
P
D
A
G
E
D
E
L
L
K
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509899
540
60910
N197
N
P
N
A
M
L
V
N
L
E
E
P
L
A
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082590
1618
184741
G1140
H
E
K
F
P
D
A
G
E
D
E
L
L
K
I
Zebra Danio
Brachydanio rerio
XP_001920847
855
96845
Q512
H
T
L
L
L
D
H
Q
D
A
I
A
P
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203784
771
87814
E428
V
D
L
S
E
E
L
E
L
Q
E
M
R
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
82.6
N.A.
58.7
N.A.
N.A.
22
N.A.
56.9
29.7
N.A.
N.A.
N.A.
N.A.
24.8
Protein Similarity:
100
N.A.
N.A.
89.4
N.A.
75.1
N.A.
N.A.
28
N.A.
74.1
40.5
N.A.
N.A.
N.A.
N.A.
36.2
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
53.3
N.A.
N.A.
6.6
N.A.
53.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
73.3
N.A.
N.A.
6.6
N.A.
73.3
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
0
0
15
0
0
43
0
0
15
0
15
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
72
0
0
29
29
0
0
0
15
0
% D
% Glu:
0
58
0
0
15
15
0
15
43
15
86
0
0
0
0
% E
% Phe:
0
0
0
58
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
29
0
0
0
0
0
15
0
% G
% His:
43
0
0
0
0
0
15
0
0
0
0
0
0
0
15
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
29
% I
% Lys:
0
0
58
0
0
0
0
0
0
0
0
0
0
58
15
% K
% Leu:
0
0
29
15
15
15
15
0
29
0
0
29
43
0
0
% L
% Met:
0
0
0
0
15
0
0
0
0
0
0
15
0
0
0
% M
% Asn:
15
0
15
0
0
0
15
15
0
15
0
0
0
0
0
% N
% Pro:
0
15
0
0
58
0
0
0
0
0
0
15
15
0
0
% P
% Gln:
0
0
0
0
0
0
0
15
0
15
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% R
% Ser:
0
0
0
15
0
0
0
15
0
15
0
0
0
0
15
% S
% Thr:
0
15
0
0
0
0
0
15
0
0
0
0
0
0
0
% T
% Val:
15
0
0
0
0
0
15
0
0
0
0
29
0
0
29
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _