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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IQGAP3 All Species: 10.61
Human Site: Y484 Identified Species: 38.89
UniProt: Q86VI3 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VI3 NP_839943.2 1631 184699 Y484 E G E N A Q R Y F D A L L K L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547533 1692 191049 Y545 E R E N A H R Y F D A L V E L
Cat Felis silvestris
Mouse Mus musculus Q9JKF1 1657 188738 Y497 E E E N C Q R Y L D E L M K L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509899 540 60910
Chicken Gallus gallus
Frog Xenopus laevis NP_001082590 1618 184741 Y458 D D E N L Q R Y I D E L I R M
Zebra Danio Brachydanio rerio XP_001920847 855 96845
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203784 771 87814
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 82.6 N.A. 58.7 N.A. N.A. 22 N.A. 56.9 29.7 N.A. N.A. N.A. N.A. 24.8
Protein Similarity: 100 N.A. N.A. 89.4 N.A. 75.1 N.A. N.A. 28 N.A. 74.1 40.5 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 N.A. N.A. 73.3 N.A. 66.6 N.A. N.A. 0 N.A. 46.6 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. 73.3 N.A. N.A. 0 N.A. 73.3 0 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 29 0 0 0 0 0 29 0 0 0 0 % A
% Cys: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 15 0 0 0 0 0 0 0 58 0 0 0 0 0 % D
% Glu: 43 15 58 0 0 0 0 0 0 0 29 0 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 % F
% Gly: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 15 0 0 0 15 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 29 0 % K
% Leu: 0 0 0 0 15 0 0 0 15 0 0 58 15 0 43 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 15 % M
% Asn: 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 43 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 15 0 0 0 0 58 0 0 0 0 0 0 15 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 58 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _