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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAPTM4B
All Species:
17.88
Human Site:
S333
Identified Species:
43.7
UniProt:
Q86VI4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VI4
NP_060877.3
370
41146
S333
Y
I
N
G
R
N
S
S
D
V
L
V
Y
V
T
Chimpanzee
Pan troglodytes
XP_508462
307
34274
D271
I
N
G
R
N
S
S
D
V
L
V
Y
V
T
S
Rhesus Macaque
Macaca mulatta
XP_001094983
233
26769
E197
I
N
N
R
N
V
P
E
I
A
V
Y
P
A
F
Dog
Lupus familis
XP_532277
393
42843
S356
Y
I
N
G
R
N
S
S
D
V
L
V
Y
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91XQ6
227
25376
V191
N
G
R
N
S
S
D
V
L
V
Y
V
T
S
N
Rat
Rattus norvegicus
Q5U1W4
227
25385
V191
N
G
R
N
S
S
D
V
L
V
Y
V
T
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506158
217
24001
S181
Y
V
S
G
R
N
T
S
D
V
L
V
Y
I
T
Chicken
Gallus gallus
Q5ZML7
229
26256
E193
I
S
N
R
N
L
P
E
I
A
V
Y
P
A
F
Frog
Xenopus laevis
NP_001121245
225
25503
S189
Y
I
N
N
R
N
S
S
D
V
L
V
Y
V
T
Zebra Danio
Brachydanio rerio
NP_956392
225
25225
T189
Y
V
S
G
R
S
T
T
E
V
L
V
Y
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.1
26.7
63.3
N.A.
56.4
57
N.A.
49.7
26.7
50.5
44.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.5
40.8
69.4
N.A.
58.9
59.4
N.A.
56.2
39.1
56.2
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
13.3
13.3
N.A.
73.3
6.6
93.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
13.3
100
N.A.
20
20
N.A.
100
13.3
93.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
20
0
0
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
20
10
40
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
20
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% F
% Gly:
0
20
10
40
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
30
30
0
0
0
0
0
0
20
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
20
10
50
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
20
50
30
30
40
0
0
0
0
0
0
0
0
20
% N
% Pro:
0
0
0
0
0
0
20
0
0
0
0
0
20
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
20
30
50
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
20
0
20
40
40
40
0
0
0
0
0
20
10
% S
% Thr:
0
0
0
0
0
0
20
10
0
0
0
0
20
10
50
% T
% Val:
0
20
0
0
0
10
0
20
10
70
30
70
10
40
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
50
0
0
0
0
0
0
0
0
0
20
30
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _