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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAPTM4B
All Species:
4.55
Human Site:
T355
Identified Species:
11.11
UniProt:
Q86VI4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VI4
NP_060877.3
370
41146
T355
L
P
P
Y
D
D
A
T
V
N
G
A
A
K
E
Chimpanzee
Pan troglodytes
XP_508462
307
34274
V293
P
P
Y
D
D
A
T
V
N
G
A
A
K
E
P
Rhesus Macaque
Macaca mulatta
XP_001094983
233
26769
V219
L
P
T
Y
E
M
A
V
K
M
P
E
K
E
P
Dog
Lupus familis
XP_532277
393
42843
T378
L
P
P
Y
D
D
A
T
V
N
G
A
A
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91XQ6
227
25376
V213
P
Y
D
D
A
T
A
V
P
S
T
A
K
E
P
Rat
Rattus norvegicus
Q5U1W4
227
25385
V213
P
Y
D
D
A
T
A
V
T
G
T
A
K
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506158
217
24001
A203
L
P
P
Y
N
D
T
A
N
G
A
A
K
E
P
Chicken
Gallus gallus
Q5ZML7
229
26256
V215
L
P
T
Y
E
M
A
V
K
M
P
E
K
E
P
Frog
Xenopus laevis
NP_001121245
225
25503
G211
L
P
H
Y
D
E
S
G
S
G
T
A
K
E
P
Zebra Danio
Brachydanio rerio
NP_956392
225
25225
I211
L
P
P
Y
E
E
A
I
A
I
P
P
K
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.1
26.7
63.3
N.A.
56.4
57
N.A.
49.7
26.7
50.5
44.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.5
40.8
69.4
N.A.
58.9
59.4
N.A.
56.2
39.1
56.2
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
26.6
100
N.A.
13.3
13.3
N.A.
40
26.6
33.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
40
100
N.A.
26.6
20
N.A.
53.3
40
53.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
10
70
10
10
0
20
70
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
30
40
30
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
30
20
0
0
0
0
0
20
0
70
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
40
20
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
20
0
0
0
80
20
0
% K
% Leu:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
20
0
0
0
20
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
20
20
0
0
0
0
0
% N
% Pro:
30
80
40
0
0
0
0
0
10
0
30
10
0
0
80
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% S
% Thr:
0
0
20
0
0
20
20
20
10
0
30
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
50
20
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
10
70
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _