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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZC3H18 All Species: 27.58
Human Site: S522 Identified Species: 67.41
UniProt: Q86VM9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VM9 NP_653205 953 106378 S522 W K D P W R R S K S P K K K L
Chimpanzee Pan troglodytes XP_001135214 955 105105 S524 W K D P W R R S K S P K K K L
Rhesus Macaque Macaca mulatta XP_001088503 718 80384 T309 R A R R R R K T S A S S A S A
Dog Lupus familis XP_546785 947 105910 R515 E W K D P W R R S K S P K K K
Cat Felis silvestris
Mouse Mus musculus Q0P678 948 105675 S518 W K D P W R R S K S P K K K L
Rat Rattus norvegicus Q6TQE1 947 105518 S517 W K D P W R R S K S P K K K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508502 950 107373 S518 W K D P W R R S K S P K K K L
Chicken Gallus gallus XP_414199 954 107254 S526 W K D P W R R S K S P K K K L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LUE5 1148 129153 S654 W N D P W C R S K S P R R R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193057 513 57454 E104 P P E E P R P E S A W E R G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.1 74.7 90.2 N.A. 90.7 90.6 N.A. 85.7 78.7 N.A. 52.6 N.A. N.A. N.A. N.A. 21.4
Protein Similarity: 100 94.5 74.9 92.8 N.A. 94.3 94.4 N.A. 89.1 84.9 N.A. 61.7 N.A. N.A. N.A. N.A. 32.7
P-Site Identity: 100 100 6.6 20 N.A. 100 100 N.A. 100 100 N.A. 60 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 26.6 20 N.A. 100 100 N.A. 100 100 N.A. 80 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 20 0 0 10 0 10 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 70 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 10 10 0 0 0 10 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 60 10 0 0 0 10 0 70 10 0 60 70 70 10 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 10 0 70 20 0 10 0 0 0 70 10 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 10 10 10 80 80 10 0 0 0 10 20 10 0 % R
% Ser: 0 0 0 0 0 0 0 70 30 70 20 10 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 70 10 0 0 70 10 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _