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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3H18
All Species:
25.76
Human Site:
S685
Identified Species:
62.96
UniProt:
Q86VM9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VM9
NP_653205
953
106378
S685
P
P
R
R
R
T
L
S
G
S
G
S
G
S
G
Chimpanzee
Pan troglodytes
XP_001135214
955
105105
S687
P
P
R
R
R
T
L
S
G
S
G
S
G
S
G
Rhesus Macaque
Macaca mulatta
XP_001088503
718
80384
L470
S
S
S
R
S
R
S
L
S
V
S
S
V
S
S
Dog
Lupus familis
XP_546785
947
105910
T676
R
S
P
P
R
R
R
T
V
S
G
S
G
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q0P678
948
105675
S681
P
P
R
R
R
T
L
S
G
S
G
S
G
S
G
Rat
Rattus norvegicus
Q6TQE1
947
105518
S680
P
P
R
R
R
T
L
S
G
S
G
S
G
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508502
950
107373
S680
P
P
R
R
R
T
L
S
G
S
I
S
G
S
G
Chicken
Gallus gallus
XP_414199
954
107254
S688
P
P
R
R
R
T
I
S
G
S
I
S
G
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LUE5
1148
129153
S863
Y
S
G
S
S
S
R
S
R
S
R
S
S
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193057
513
57454
D265
R
S
P
G
G
L
A
D
K
R
R
D
E
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
74.7
90.2
N.A.
90.7
90.6
N.A.
85.7
78.7
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
94.5
74.9
92.8
N.A.
94.3
94.4
N.A.
89.1
84.9
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
32.7
P-Site Identity:
100
100
20
46.6
N.A.
100
100
N.A.
93.3
80
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
20
53.3
N.A.
100
100
N.A.
93.3
86.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
10
10
0
0
0
60
0
50
0
70
0
60
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
20
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
50
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
60
60
20
10
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
20
0
60
70
70
20
20
0
10
10
20
0
0
10
0
% R
% Ser:
10
40
10
10
20
10
10
70
10
80
10
90
10
90
10
% S
% Thr:
0
0
0
0
0
60
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _