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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3H18
All Species:
6.06
Human Site:
S74
Identified Species:
14.81
UniProt:
Q86VM9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VM9
NP_653205
953
106378
S74
S
D
E
E
D
R
A
S
E
P
K
S
Q
D
Q
Chimpanzee
Pan troglodytes
XP_001135214
955
105105
S74
S
D
E
E
D
R
A
S
E
P
K
S
Q
D
Q
Rhesus Macaque
Macaca mulatta
XP_001088503
718
80384
P8
M
N
C
R
F
I
H
P
G
V
N
D
K
G
N
Dog
Lupus familis
XP_546785
947
105910
Q75
S
D
E
E
D
Q
D
Q
E
S
E
A
Q
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q0P678
948
105675
K74
E
D
R
A
S
E
P
K
S
Q
D
Q
D
S
E
Rat
Rattus norvegicus
Q6TQE1
947
105518
S74
D
Q
A
S
E
P
K
S
Q
D
Q
D
S
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508502
950
107373
E74
D
E
E
D
H
L
S
E
T
K
S
Q
D
S
D
Chicken
Gallus gallus
XP_414199
954
107254
P89
Q
G
G
E
L
K
S
P
P
P
R
K
G
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LUE5
1148
129153
E174
E
L
E
E
E
E
D
E
E
E
E
R
R
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193057
513
57454
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
74.7
90.2
N.A.
90.7
90.6
N.A.
85.7
78.7
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
94.5
74.9
92.8
N.A.
94.3
94.4
N.A.
89.1
84.9
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
32.7
P-Site Identity:
100
100
0
53.3
N.A.
6.6
6.6
N.A.
6.6
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
13.3
73.3
N.A.
13.3
33.3
N.A.
26.6
46.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
20
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
40
0
10
30
0
20
0
0
10
10
20
20
30
10
% D
% Glu:
20
10
50
50
20
20
0
20
40
10
20
0
0
20
20
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
0
0
10
0
0
0
10
10
0
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
10
10
0
10
20
10
10
0
0
% K
% Leu:
0
10
0
0
10
10
0
0
0
0
0
0
0
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% N
% Pro:
0
0
0
0
0
10
10
20
10
30
0
0
0
0
0
% P
% Gln:
10
10
0
0
0
10
0
10
10
10
10
20
30
0
20
% Q
% Arg:
0
0
10
10
0
20
0
0
0
0
10
10
10
10
10
% R
% Ser:
30
0
0
10
10
0
20
30
10
10
10
20
10
20
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _