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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3H18
All Species:
28.48
Human Site:
S746
Identified Species:
69.63
UniProt:
Q86VM9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VM9
NP_653205
953
106378
S746
V
S
S
A
S
S
R
S
P
A
P
A
Q
T
R
Chimpanzee
Pan troglodytes
XP_001135214
955
105105
S748
V
S
S
A
S
S
R
S
P
A
P
A
Q
T
R
Rhesus Macaque
Macaca mulatta
XP_001088503
718
80384
K531
S
K
K
E
D
G
V
K
E
E
K
R
K
R
D
Dog
Lupus familis
XP_546785
947
105910
S737
V
S
S
A
S
S
R
S
P
T
P
A
Q
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q0P678
948
105675
S742
V
S
S
A
S
S
R
S
P
T
P
A
Q
T
K
Rat
Rattus norvegicus
Q6TQE1
947
105518
S741
V
S
S
A
S
S
R
S
P
T
P
A
Q
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508502
950
107373
S741
V
S
S
A
S
S
R
S
P
T
P
A
Q
P
K
Chicken
Gallus gallus
XP_414199
954
107254
S749
V
S
S
A
S
S
R
S
P
T
P
A
Q
Q
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LUE5
1148
129153
S924
V
S
S
A
S
S
R
S
P
T
P
G
H
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193057
513
57454
G326
K
K
G
R
S
T
V
G
G
G
R
R
P
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
74.7
90.2
N.A.
90.7
90.6
N.A.
85.7
78.7
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
94.5
74.9
92.8
N.A.
94.3
94.4
N.A.
89.1
84.9
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
32.7
P-Site Identity:
100
100
0
86.6
N.A.
86.6
86.6
N.A.
80
80
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
86.6
86.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
80
0
0
0
0
0
20
0
70
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
10
0
0
0
0
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
10
0
10
10
10
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
20
10
0
0
0
0
10
0
0
10
0
10
0
50
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
80
0
80
0
10
20
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
70
10
0
% Q
% Arg:
0
0
0
10
0
0
80
0
0
0
10
20
0
20
30
% R
% Ser:
10
80
80
0
90
80
0
80
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
60
0
0
0
50
0
% T
% Val:
80
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _