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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3H18
All Species:
6.06
Human Site:
S774
Identified Species:
14.81
UniProt:
Q86VM9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VM9
NP_653205
953
106378
S774
E
E
K
R
K
R
D
S
S
T
Q
P
P
K
S
Chimpanzee
Pan troglodytes
XP_001135214
955
105105
S776
E
E
K
R
K
R
D
S
S
T
Q
P
P
K
S
Rhesus Macaque
Macaca mulatta
XP_001088503
718
80384
P559
G
G
K
S
S
Q
Q
P
S
T
P
Q
Q
A
P
Dog
Lupus familis
XP_546785
947
105910
P765
E
D
K
R
K
R
D
P
S
A
Q
L
P
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q0P678
948
105675
P770
E
E
K
R
R
R
D
P
S
A
Q
P
P
K
S
Rat
Rattus norvegicus
Q6TQE1
947
105518
P769
E
E
K
R
K
R
D
P
S
A
Q
P
P
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508502
950
107373
V769
E
E
K
R
K
R
E
V
S
S
Q
P
P
K
S
Chicken
Gallus gallus
XP_414199
954
107254
V777
E
E
K
R
K
R
D
V
P
A
Q
L
K
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LUE5
1148
129153
K952
E
R
G
K
P
P
K
K
D
E
P
F
K
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193057
513
57454
S354
S
S
R
S
R
S
R
S
D
S
R
S
R
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
74.7
90.2
N.A.
90.7
90.6
N.A.
85.7
78.7
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
94.5
74.9
92.8
N.A.
94.3
94.4
N.A.
89.1
84.9
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
32.7
P-Site Identity:
100
100
20
73.3
N.A.
80
86.6
N.A.
80
53.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
26.6
80
N.A.
86.6
86.6
N.A.
93.3
60
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
40
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
60
0
20
0
0
0
0
10
0
% D
% Glu:
80
60
0
0
0
0
10
0
0
10
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
80
10
60
0
10
10
0
0
0
0
20
60
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
10
0
40
10
0
20
50
60
0
10
% P
% Gln:
0
0
0
0
0
10
10
0
0
0
70
10
10
0
0
% Q
% Arg:
0
10
10
70
20
70
10
0
0
0
10
0
10
0
10
% R
% Ser:
10
10
0
20
10
10
0
30
70
20
0
10
0
20
60
% S
% Thr:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _