Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZC3H18 All Species: 6.06
Human Site: S774 Identified Species: 14.81
UniProt: Q86VM9 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VM9 NP_653205 953 106378 S774 E E K R K R D S S T Q P P K S
Chimpanzee Pan troglodytes XP_001135214 955 105105 S776 E E K R K R D S S T Q P P K S
Rhesus Macaque Macaca mulatta XP_001088503 718 80384 P559 G G K S S Q Q P S T P Q Q A P
Dog Lupus familis XP_546785 947 105910 P765 E D K R K R D P S A Q L P K S
Cat Felis silvestris
Mouse Mus musculus Q0P678 948 105675 P770 E E K R R R D P S A Q P P K S
Rat Rattus norvegicus Q6TQE1 947 105518 P769 E E K R K R D P S A Q P P K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508502 950 107373 V769 E E K R K R E V S S Q P P K S
Chicken Gallus gallus XP_414199 954 107254 V777 E E K R K R D V P A Q L K S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LUE5 1148 129153 K952 E R G K P P K K D E P F K D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193057 513 57454 S354 S S R S R S R S D S R S R S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.1 74.7 90.2 N.A. 90.7 90.6 N.A. 85.7 78.7 N.A. 52.6 N.A. N.A. N.A. N.A. 21.4
Protein Similarity: 100 94.5 74.9 92.8 N.A. 94.3 94.4 N.A. 89.1 84.9 N.A. 61.7 N.A. N.A. N.A. N.A. 32.7
P-Site Identity: 100 100 20 73.3 N.A. 80 86.6 N.A. 80 53.3 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 26.6 80 N.A. 86.6 86.6 N.A. 93.3 60 N.A. 13.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 40 0 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 60 0 20 0 0 0 0 10 0 % D
% Glu: 80 60 0 0 0 0 10 0 0 10 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 10 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 80 10 60 0 10 10 0 0 0 0 20 60 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 10 0 40 10 0 20 50 60 0 10 % P
% Gln: 0 0 0 0 0 10 10 0 0 0 70 10 10 0 0 % Q
% Arg: 0 10 10 70 20 70 10 0 0 0 10 0 10 0 10 % R
% Ser: 10 10 0 20 10 10 0 30 70 20 0 10 0 20 60 % S
% Thr: 0 0 0 0 0 0 0 0 0 30 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _