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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZC3H18 All Species: 6.06
Human Site: S95 Identified Species: 14.81
UniProt: Q86VM9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VM9 NP_653205 953 106378 S95 L S R G P T S S P C E E E G D
Chimpanzee Pan troglodytes XP_001135214 955 105105 S95 L S R G P T S S P C E E E G D
Rhesus Macaque Macaca mulatta XP_001088503 718 80384 G29 A D P F P P N G A P P L G P H
Dog Lupus familis XP_546785 947 105910 D96 P P H V E E G D G G E E E H T
Cat Felis silvestris
Mouse Mus musculus Q0P678 948 105675 E95 G P A G S P C E E G D D V E E
Rat Rattus norvegicus Q6TQE1 947 105518 E95 P A G S P C E E G D D A E E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508502 950 107373 H95 L L K S S P L H E E E E E E E
Chicken Gallus gallus XP_414199 954 107254 V110 L G D E A S S V T R E L D E H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LUE5 1148 129153 S195 V S D L K D E S S V S R D L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193057 513 57454
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.1 74.7 90.2 N.A. 90.7 90.6 N.A. 85.7 78.7 N.A. 52.6 N.A. N.A. N.A. N.A. 21.4
Protein Similarity: 100 94.5 74.9 92.8 N.A. 94.3 94.4 N.A. 89.1 84.9 N.A. 61.7 N.A. N.A. N.A. N.A. 32.7
P-Site Identity: 100 100 6.6 20 N.A. 6.6 20 N.A. 26.6 20 N.A. 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 13.3 20 N.A. 26.6 33.3 N.A. 40 33.3 N.A. 33.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 10 0 0 0 10 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 10 10 0 0 20 0 0 0 0 0 % C
% Asp: 0 10 20 0 0 10 0 10 0 10 20 10 20 0 40 % D
% Glu: 0 0 0 10 10 10 20 20 20 10 50 40 50 40 20 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 10 30 0 0 10 10 20 20 0 0 10 20 0 % G
% His: 0 0 10 0 0 0 0 10 0 0 0 0 0 10 20 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 40 10 0 10 0 0 10 0 0 0 0 20 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 20 20 10 0 40 30 0 0 20 10 10 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 20 0 0 0 0 0 0 10 0 10 0 0 0 % R
% Ser: 0 30 0 20 20 10 30 30 10 0 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 20 0 0 10 0 0 0 0 0 10 % T
% Val: 10 0 0 10 0 0 0 10 0 10 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _