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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS36
All Species:
35.76
Human Site:
S123
Identified Species:
56.19
UniProt:
Q86VN1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VN1
NP_057159.2
386
43817
S123
I
E
F
Y
R
R
L
S
E
E
M
T
Q
R
R
Chimpanzee
Pan troglodytes
XP_001134797
377
42708
S114
I
E
F
Y
R
R
L
S
E
E
M
T
Q
R
R
Rhesus Macaque
Macaca mulatta
XP_001082759
386
43783
S123
I
E
F
Y
R
R
L
S
E
E
M
T
Q
R
R
Dog
Lupus familis
XP_534484
386
43758
S123
I
E
F
Y
R
R
L
S
E
E
M
T
Q
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91XD6
386
43717
S123
I
E
F
Y
R
R
L
S
E
E
M
T
Q
R
R
Rat
Rattus norvegicus
P0C0A2
386
43699
S123
I
E
F
Y
R
R
L
S
E
E
M
T
Q
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513182
358
40422
Q113
I
P
T
A
Q
S
L
Q
I
N
R
G
S
Q
P
Chicken
Gallus gallus
XP_417077
386
43557
S123
I
E
F
F
R
R
F
S
E
E
I
T
Q
R
R
Frog
Xenopus laevis
Q6DDF4
388
43900
A123
I
E
F
Q
R
R
L
A
E
E
L
T
Q
R
R
Zebra Danio
Brachydanio rerio
Q7ZVK4
382
43262
T123
I
E
F
Y
R
R
L
T
E
E
M
T
Q
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU87
399
44195
R129
V
E
F
H
S
A
L
R
E
T
L
N
A
R
V
Honey Bee
Apis mellifera
XP_395542
402
45958
S129
P
N
F
H
T
H
L
S
D
T
I
M
R
R
I
Nematode Worm
Caenorhab. elegans
NP_505798
383
42691
E123
D
D
F
F
K
K
Y
E
D
A
V
R
R
K
T
Sea Urchin
Strong. purpuratus
XP_796608
328
36233
E105
G
I
E
R
K
L
E
E
K
R
K
E
T
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF81
440
49015
S131
G
D
F
D
G
F
L
S
K
L
W
E
C
W
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
99.4
98.9
N.A.
95.8
95.8
N.A.
86.7
89.6
86
84.1
N.A.
46.6
48.7
41.9
51.3
Protein Similarity:
100
97.6
100
99.2
N.A.
98.9
98.6
N.A.
89.9
95
92.7
92.7
N.A.
66.9
69.6
64.7
66.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
80
80
86.6
N.A.
33.3
26.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
93.3
93.3
100
N.A.
53.3
53.3
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
0
7
0
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
14
0
7
0
0
0
0
14
0
0
0
0
7
0
% D
% Glu:
0
67
7
0
0
0
7
14
67
60
0
14
0
0
0
% E
% Phe:
0
0
87
14
0
7
7
0
0
0
0
0
0
0
0
% F
% Gly:
14
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
14
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
7
0
0
0
0
0
0
7
0
14
0
0
0
7
% I
% Lys:
0
0
0
0
14
7
0
0
14
0
7
0
0
14
0
% K
% Leu:
0
0
0
0
0
7
80
0
0
7
14
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
47
7
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
7
0
7
0
0
0
% N
% Pro:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
7
7
0
0
7
0
0
0
0
60
7
0
% Q
% Arg:
0
0
0
7
60
60
0
7
0
7
7
7
14
67
67
% R
% Ser:
0
0
0
0
7
7
0
60
0
0
0
0
7
0
0
% S
% Thr:
0
0
7
0
7
0
0
7
0
14
0
60
7
0
14
% T
% Val:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% W
% Tyr:
0
0
0
47
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _