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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS36
All Species:
28.48
Human Site:
S137
Identified Species:
44.76
UniProt:
Q86VN1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VN1
NP_057159.2
386
43817
S137
R
W
E
N
M
P
V
S
Q
S
L
Q
T
N
R
Chimpanzee
Pan troglodytes
XP_001134797
377
42708
S128
R
W
E
N
M
P
V
S
Q
S
L
Q
T
N
R
Rhesus Macaque
Macaca mulatta
XP_001082759
386
43783
S137
R
W
E
N
M
P
V
S
Q
S
L
Q
T
N
R
Dog
Lupus familis
XP_534484
386
43758
S137
R
W
E
N
M
P
V
S
Q
S
L
Q
T
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91XD6
386
43717
S137
R
W
E
T
V
P
V
S
Q
S
L
Q
T
N
K
Rat
Rattus norvegicus
P0C0A2
386
43699
S137
R
W
E
T
V
P
V
S
Q
S
L
Q
T
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513182
358
40422
G127
P
G
R
I
R
A
V
G
I
V
G
I
E
R
K
Chicken
Gallus gallus
XP_417077
386
43557
G137
R
W
E
N
M
P
A
G
Q
T
I
Q
V
N
K
Frog
Xenopus laevis
Q6DDF4
388
43900
S137
R
W
E
R
L
S
A
S
A
S
P
S
M
Q
M
Zebra Danio
Brachydanio rerio
Q7ZVK4
382
43262
S137
R
W
E
N
T
P
V
S
Q
P
I
P
T
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU87
399
44195
S143
V
W
E
I
L
L
T
S
E
I
I
I
N
G
V
Honey Bee
Apis mellifera
XP_395542
402
45958
M143
I
W
E
L
T
P
I
M
P
L
N
H
P
D
T
Nematode Worm
Caenorhab. elegans
NP_505798
383
42691
G137
T
W
Q
R
S
S
S
G
S
S
S
S
G
S
R
Sea Urchin
Strong. purpuratus
XP_796608
328
36233
E119
T
N
I
D
K
A
F
E
D
L
G
E
L
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF81
440
49015
E145
R
G
R
A
W
E
E
E
E
K
S
E
S
E
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
99.4
98.9
N.A.
95.8
95.8
N.A.
86.7
89.6
86
84.1
N.A.
46.6
48.7
41.9
51.3
Protein Similarity:
100
97.6
100
99.2
N.A.
98.9
98.6
N.A.
89.9
95
92.7
92.7
N.A.
66.9
69.6
64.7
66.5
P-Site Identity:
100
100
100
100
N.A.
80
73.3
N.A.
6.6
60
33.3
60
N.A.
20
20
20
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
13.3
80
40
66.6
N.A.
40
33.3
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
14
14
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
7
0
0
0
0
7
0
% D
% Glu:
0
0
74
0
0
7
7
14
14
0
0
14
7
7
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
0
0
0
0
0
20
0
0
14
0
7
14
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
7
0
7
14
0
0
7
0
7
7
20
14
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
0
0
7
0
0
0
7
34
% K
% Leu:
0
0
0
7
14
7
0
0
0
14
40
0
7
0
0
% L
% Met:
0
0
0
0
34
0
0
7
0
0
0
0
7
7
7
% M
% Asn:
0
7
0
40
0
0
0
0
0
0
7
0
7
40
0
% N
% Pro:
7
0
0
0
0
60
0
0
7
7
7
7
7
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
54
0
0
47
0
7
0
% Q
% Arg:
67
0
14
14
7
0
0
0
0
0
0
0
0
7
34
% R
% Ser:
0
0
0
0
7
14
7
60
7
54
14
14
7
7
0
% S
% Thr:
14
0
0
14
14
0
7
0
0
7
0
0
47
0
20
% T
% Val:
7
0
0
0
14
0
54
0
0
7
0
0
7
0
7
% V
% Trp:
0
80
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _