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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS36
All Species:
26.36
Human Site:
T39
Identified Species:
41.43
UniProt:
Q86VN1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VN1
NP_057159.2
386
43817
T39
K
I
K
F
D
A
G
T
L
L
L
S
T
H
R
Chimpanzee
Pan troglodytes
XP_001134797
377
42708
I39
L
L
S
T
H
R
L
I
W
R
D
Q
K
N
H
Rhesus Macaque
Macaca mulatta
XP_001082759
386
43783
T39
K
I
K
F
D
A
G
T
L
L
L
S
T
H
R
Dog
Lupus familis
XP_534484
386
43758
T39
K
I
K
F
D
A
G
T
L
L
L
S
T
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91XD6
386
43717
T39
K
I
K
F
D
A
G
T
L
L
L
S
T
H
R
Rat
Rattus norvegicus
P0C0A2
386
43699
T39
K
I
K
F
D
A
G
T
L
L
L
S
T
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513182
358
40422
V39
A
I
P
L
S
Q
I
V
F
I
E
E
Q
A
A
Chicken
Gallus gallus
XP_417077
386
43557
V39
K
V
K
F
D
S
G
V
L
L
L
S
T
H
R
Frog
Xenopus laevis
Q6DDF4
388
43900
T39
K
T
K
F
D
S
G
T
L
L
L
T
T
H
R
Zebra Danio
Brachydanio rerio
Q7ZVK4
382
43262
G39
K
A
K
L
D
V
G
G
V
V
L
S
T
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU87
399
44195
E39
K
T
D
F
E
D
G
E
V
V
L
T
T
H
R
Honey Bee
Apis mellifera
XP_395542
402
45958
E39
K
T
N
F
E
S
G
E
L
V
L
T
S
H
R
Nematode Worm
Caenorhab. elegans
NP_505798
383
42691
T39
Q
T
N
F
E
Q
G
T
A
S
L
T
M
Q
R
Sea Urchin
Strong. purpuratus
XP_796608
328
36233
A32
V
V
V
H
L
N
A
A
P
P
N
K
N
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF81
440
49015
S39
V
E
C
F
L
L
S
S
I
D
I
D
S
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
99.4
98.9
N.A.
95.8
95.8
N.A.
86.7
89.6
86
84.1
N.A.
46.6
48.7
41.9
51.3
Protein Similarity:
100
97.6
100
99.2
N.A.
98.9
98.6
N.A.
89.9
95
92.7
92.7
N.A.
66.9
69.6
64.7
66.5
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
6.6
80
80
60
N.A.
46.6
46.6
33.3
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
13.3
93.3
93.3
73.3
N.A.
73.3
80
53.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
34
7
7
7
0
0
0
0
7
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
54
7
0
0
0
7
7
7
0
0
7
% D
% Glu:
0
7
0
0
20
0
0
14
0
0
7
7
0
7
0
% E
% Phe:
0
0
0
74
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
74
7
0
0
0
0
0
0
7
% G
% His:
0
0
0
7
7
0
0
0
0
0
0
0
0
67
7
% H
% Ile:
0
40
0
0
0
0
7
7
7
7
7
0
0
0
0
% I
% Lys:
67
0
54
0
0
0
0
0
0
0
0
7
7
0
0
% K
% Leu:
7
7
0
14
14
7
7
0
54
47
74
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
14
0
0
7
0
0
0
0
7
0
7
7
0
% N
% Pro:
0
0
7
0
0
0
0
0
7
7
0
0
0
7
0
% P
% Gln:
7
0
0
0
0
14
0
0
0
0
0
7
7
7
0
% Q
% Arg:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
74
% R
% Ser:
0
0
7
0
7
20
7
7
0
7
0
47
14
0
0
% S
% Thr:
0
27
0
7
0
0
0
47
0
0
0
27
60
0
0
% T
% Val:
14
14
7
0
0
7
0
14
14
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _