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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS36 All Species: 41.52
Human Site: Y241 Identified Species: 65.24
UniProt: Q86VN1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VN1 NP_057159.2 386 43817 Y241 T Y G S G T Q Y H M Q L A K Q
Chimpanzee Pan troglodytes XP_001134797 377 42708 Y232 T Y G S G T Q Y H M Q L A K Q
Rhesus Macaque Macaca mulatta XP_001082759 386 43783 Y241 T Y G S G T Q Y H M Q L A K Q
Dog Lupus familis XP_534484 386 43758 Y241 T Y G S G T Q Y H M Q L A K Q
Cat Felis silvestris
Mouse Mus musculus Q91XD6 386 43717 Y241 T Y G S G T Q Y H M Q L A K Q
Rat Rattus norvegicus P0C0A2 386 43699 Y241 T Y G S G T Q Y H M Q L A K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513182 358 40422 Q220 Y H M Q L A K Q L V G I L Q V
Chicken Gallus gallus XP_417077 386 43557 Y241 T H G S G T H Y H M Q L A K Q
Frog Xenopus laevis Q6DDF4 388 43900 Y243 T H G S G T H Y H M Q L A K Q
Zebra Danio Brachydanio rerio Q7ZVK4 382 43262 Y241 T H G S G T Q Y H I Q L A K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VU87 399 44195 Y257 N F T S N S A Y F S S L A R Q
Honey Bee Apis mellifera XP_395542 402 45958 Y256 A Y K N S N E Y F K Q L A K Q
Nematode Worm Caenorhab. elegans NP_505798 383 42691 E239 T F V G S D S E Y F Q K L A K
Sea Urchin Strong. purpuratus XP_796608 328 36233 Y210 M M A I T D V Y C R I N R A R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FF81 440 49015 Q268 S A G A L Y H Q E L S R Q L A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 99.4 98.9 N.A. 95.8 95.8 N.A. 86.7 89.6 86 84.1 N.A. 46.6 48.7 41.9 51.3
Protein Similarity: 100 97.6 100 99.2 N.A. 98.9 98.6 N.A. 89.9 95 92.7 92.7 N.A. 66.9 69.6 64.7 66.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 86.6 86.6 86.6 N.A. 33.3 46.6 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 93.3 93.3 100 N.A. 53.3 60 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 51.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 7 0 7 7 0 0 0 0 0 74 14 7 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 7 7 7 0 0 0 0 0 0 % E
% Phe: 0 14 0 0 0 0 0 0 14 7 0 0 0 0 0 % F
% Gly: 0 0 67 7 60 0 0 0 0 0 7 0 0 0 0 % G
% His: 0 27 0 0 0 0 20 0 60 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 7 7 7 0 0 0 % I
% Lys: 0 0 7 0 0 0 7 0 0 7 0 7 0 67 7 % K
% Leu: 0 0 0 0 14 0 0 0 7 7 0 74 14 7 0 % L
% Met: 7 7 7 0 0 0 0 0 0 54 0 0 0 0 0 % M
% Asn: 7 0 0 7 7 7 0 0 0 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 0 47 14 0 0 74 0 7 7 74 % Q
% Arg: 0 0 0 0 0 0 0 0 0 7 0 7 7 7 7 % R
% Ser: 7 0 0 67 14 7 7 0 0 7 14 0 0 0 0 % S
% Thr: 67 0 7 0 7 60 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 7 0 0 0 7 0 0 7 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 47 0 0 0 7 0 80 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _