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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS2
All Species:
13.33
Human Site:
S154
Identified Species:
26.67
UniProt:
Q86VP3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VP3
NP_001094383.1
889
97702
S154
S
E
G
G
Q
V
L
S
L
C
S
S
I
K
E
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
G233
N
E
G
A
L
V
L
G
L
H
S
N
V
K
D
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
G232
N
E
G
A
L
V
L
G
L
H
S
N
V
K
D
Dog
Lupus familis
XP_548006
1096
119669
S359
S
E
G
G
Q
V
L
S
L
C
S
S
I
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3V3Q7
862
94918
A137
K
E
A
S
V
K
V
A
E
I
W
I
V
S
L
Rat
Rattus norvegicus
O88588
961
104682
G231
N
E
G
A
L
V
L
G
L
H
S
N
V
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
Chicken
Gallus gallus
XP_422219
894
99206
S157
T
E
G
G
Q
V
L
S
L
F
S
N
I
K
E
Frog
Xenopus laevis
NP_001124414
878
97767
S151
T
E
G
S
Q
V
L
S
L
F
S
N
M
K
E
Zebra Danio
Brachydanio rerio
NP_001116223
878
97631
A154
A
E
G
G
Q
V
L
A
L
C
S
N
Q
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120982
812
90475
Y124
K
N
R
T
M
L
G
Y
K
T
L
A
E
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
R28
F
A
T
W
E
V
E
R
T
S
P
N
C
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.7
53.7
73.4
N.A.
91.1
54.6
N.A.
46.9
85.6
82.1
74.5
N.A.
N.A.
38.9
N.A.
31.8
Protein Similarity:
100
68.3
67.4
76.3
N.A.
93.3
68.5
N.A.
52.4
91.2
89.8
84.6
N.A.
N.A.
57.5
N.A.
47.5
P-Site Identity:
100
46.6
46.6
100
N.A.
6.6
46.6
N.A.
0
80
66.6
73.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
73.3
73.3
100
N.A.
26.6
73.3
N.A.
0
93.3
86.6
93.3
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
25
0
0
0
17
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
25
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% D
% Glu:
0
75
0
0
9
0
9
0
9
0
0
0
9
0
42
% E
% Phe:
9
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% F
% Gly:
0
0
67
34
0
0
9
25
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
9
25
9
0
% I
% Lys:
17
0
0
0
0
9
0
0
9
0
0
0
0
67
0
% K
% Leu:
0
0
0
0
25
9
67
0
67
0
9
0
0
0
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
25
9
0
0
0
0
0
0
0
0
0
59
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% P
% Gln:
0
0
0
0
42
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
17
0
0
17
0
0
0
34
0
9
67
17
0
9
0
% S
% Thr:
17
0
9
9
0
0
0
0
9
9
0
0
0
0
0
% T
% Val:
0
0
0
0
9
75
9
0
0
0
0
0
34
0
9
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _