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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PACS2 All Species: 22.73
Human Site: S34 Identified Species: 45.45
UniProt: Q86VP3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VP3 NP_001094383.1 889 97702 S34 T W E V D G S S P S C V P R L
Chimpanzee Pan troglodytes XP_001170787 963 104910 S113 T W E V D R S S S S C V P R L
Rhesus Macaque Macaca mulatta XP_001111390 962 105061 R112 D H E V R R S R P S C L T R L
Dog Lupus familis XP_548006 1096 119669 S224 T F A P R G G S C L H P S T F
Cat Felis silvestris
Mouse Mus musculus Q3V3Q7 862 94918 N23 L N T P V P M N L F A T W E V
Rat Rattus norvegicus O88588 961 104682 S111 T W E V D R S S S S C V P R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517191 517 58756
Chicken Gallus gallus XP_422219 894 99206 S37 T W E I D G S S P S C V P R L
Frog Xenopus laevis NP_001124414 878 97767 S31 T W E I D G S S P S C I P R L
Zebra Danio Brachydanio rerio NP_001116223 878 97631 S34 T W E I D G S S P N C I P R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120982 812 90475 A11 R T K T T A P A T R P V P M K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796424 717 79113
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.7 53.7 73.4 N.A. 91.1 54.6 N.A. 46.9 85.6 82.1 74.5 N.A. N.A. 38.9 N.A. 31.8
Protein Similarity: 100 68.3 67.4 76.3 N.A. 93.3 68.5 N.A. 52.4 91.2 89.8 84.6 N.A. N.A. 57.5 N.A. 47.5
P-Site Identity: 100 86.6 53.3 20 N.A. 0 86.6 N.A. 0 93.3 86.6 80 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 86.6 60 26.6 N.A. 13.3 86.6 N.A. 0 100 100 100 N.A. N.A. 26.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 9 0 9 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 59 0 0 0 0 % C
% Asp: 9 0 0 0 50 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 59 0 0 0 0 0 0 0 0 0 0 9 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 42 9 0 0 0 0 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 25 0 0 0 0 0 0 0 17 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 9 0 0 0 0 0 0 0 9 9 0 9 0 0 59 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % M
% Asn: 0 9 0 0 0 0 0 9 0 9 0 0 0 0 0 % N
% Pro: 0 0 0 17 0 9 9 0 42 0 9 9 59 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 17 25 0 9 0 9 0 0 0 59 0 % R
% Ser: 0 0 0 0 0 0 59 59 17 50 0 0 9 0 0 % S
% Thr: 59 9 9 9 9 0 0 0 9 0 0 9 9 9 0 % T
% Val: 0 0 0 34 9 0 0 0 0 0 0 42 0 0 9 % V
% Trp: 0 50 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _