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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS2
All Species:
6.36
Human Site:
S370
Identified Species:
12.73
UniProt:
Q86VP3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VP3
NP_001094383.1
889
97702
S370
R
Q
P
S
D
S
V
S
D
T
V
A
L
G
V
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
K446
K
I
K
S
T
W
I
K
N
Q
D
D
S
L
T
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
K445
K
F
K
S
T
W
I
K
N
Q
D
D
S
L
T
Dog
Lupus familis
XP_548006
1096
119669
S575
R
Q
P
S
D
S
V
S
D
T
V
T
H
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3V3Q7
862
94918
V340
K
Q
Q
L
S
D
S
V
S
D
T
V
A
L
S
Rat
Rattus norvegicus
O88588
961
104682
K444
K
V
K
S
T
W
I
K
N
Q
D
D
S
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
R27
E
S
S
R
P
R
D
R
N
R
R
L
T
P
R
Chicken
Gallus gallus
XP_422219
894
99206
S373
K
H
T
D
D
S
I
S
D
T
V
S
F
L
V
Frog
Xenopus laevis
NP_001124414
878
97767
P360
R
R
T
S
G
P
K
P
P
S
D
C
V
S
D
Zebra Danio
Brachydanio rerio
NP_001116223
878
97631
D363
A
G
G
K
F
Q
M
D
N
E
S
D
R
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120982
812
90475
P322
S
S
R
S
L
L
A
P
P
H
S
E
R
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
Q226
T
R
Q
R
N
F
K
Q
K
F
I
A
L
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.7
53.7
73.4
N.A.
91.1
54.6
N.A.
46.9
85.6
82.1
74.5
N.A.
N.A.
38.9
N.A.
31.8
Protein Similarity:
100
68.3
67.4
76.3
N.A.
93.3
68.5
N.A.
52.4
91.2
89.8
84.6
N.A.
N.A.
57.5
N.A.
47.5
P-Site Identity:
100
6.6
6.6
73.3
N.A.
6.6
6.6
N.A.
0
46.6
13.3
0
N.A.
N.A.
20
N.A.
13.3
P-Site Similarity:
100
26.6
26.6
73.3
N.A.
13.3
26.6
N.A.
6.6
66.6
33.3
13.3
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
0
0
0
0
17
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
9
25
9
9
9
25
9
34
34
0
0
9
% D
% Glu:
9
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% E
% Phe:
0
9
0
0
9
9
0
0
0
9
0
0
9
0
0
% F
% Gly:
0
9
9
0
9
0
0
0
0
0
0
0
0
17
0
% G
% His:
0
9
0
0
0
0
0
0
0
9
0
0
9
0
0
% H
% Ile:
0
9
0
0
0
0
34
0
0
0
9
0
0
0
0
% I
% Lys:
42
0
25
9
0
0
17
25
9
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
9
9
0
0
0
0
0
9
17
50
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
42
0
0
0
0
0
0
% N
% Pro:
0
0
17
0
9
9
0
17
17
0
0
0
0
9
0
% P
% Gln:
0
25
17
0
0
9
0
9
0
25
0
0
0
0
0
% Q
% Arg:
25
17
9
17
0
9
0
9
0
9
9
0
17
0
17
% R
% Ser:
9
17
9
59
9
25
9
25
9
9
17
9
25
17
17
% S
% Thr:
9
0
17
0
25
0
0
0
0
25
9
9
9
0
34
% T
% Val:
0
9
0
0
0
0
17
9
0
0
25
9
9
9
25
% V
% Trp:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _