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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS2
All Species:
7.88
Human Site:
S390
Identified Species:
15.76
UniProt:
Q86VP3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VP3
NP_001094383.1
889
97702
S390
H
P
G
Q
P
E
D
S
P
E
A
E
A
S
T
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
M465
L
E
I
T
D
Q
D
M
F
G
D
A
S
T
S
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
M464
L
E
I
T
D
Q
D
M
F
G
D
A
S
T
S
Dog
Lupus familis
XP_548006
1096
119669
S595
Q
P
A
Q
P
E
E
S
P
E
V
E
T
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3V3Q7
862
94918
S361
P
S
G
Q
P
E
D
S
P
E
A
E
T
S
T
Rat
Rattus norvegicus
O88588
961
104682
M463
L
E
I
T
D
Q
D
M
F
G
D
A
S
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
C44
A
G
F
R
A
K
L
C
P
L
F
R
F
T
D
Chicken
Gallus gallus
XP_422219
894
99206
V395
R
S
N
Q
Q
A
E
V
Q
E
A
E
L
P
A
Frog
Xenopus laevis
NP_001124414
878
97767
A378
L
E
A
P
Q
Q
E
A
Q
D
A
E
L
S
T
Zebra Danio
Brachydanio rerio
NP_001116223
878
97631
T381
P
E
V
V
T
P
T
T
E
L
E
M
M
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120982
812
90475
R339
Q
S
D
D
S
S
R
R
A
D
S
D
S
H
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
T244
V
A
S
D
E
S
D
T
E
P
Y
P
F
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.7
53.7
73.4
N.A.
91.1
54.6
N.A.
46.9
85.6
82.1
74.5
N.A.
N.A.
38.9
N.A.
31.8
Protein Similarity:
100
68.3
67.4
76.3
N.A.
93.3
68.5
N.A.
52.4
91.2
89.8
84.6
N.A.
N.A.
57.5
N.A.
47.5
P-Site Identity:
100
6.6
6.6
60
N.A.
80
6.6
N.A.
6.6
26.6
26.6
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
33.3
33.3
66.6
N.A.
80
33.3
N.A.
26.6
33.3
53.3
13.3
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
0
9
9
0
9
9
0
34
25
9
0
17
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
17
25
0
50
0
0
17
25
9
0
9
17
% D
% Glu:
0
42
0
0
9
25
25
0
17
34
9
42
0
9
0
% E
% Phe:
0
0
9
0
0
0
0
0
25
0
9
0
17
0
0
% F
% Gly:
0
9
17
0
0
0
0
0
0
25
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
34
0
0
0
0
0
9
0
0
17
0
0
17
0
0
% L
% Met:
0
0
0
0
0
0
0
25
0
0
0
9
9
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
17
17
0
9
25
9
0
0
34
9
0
9
0
9
9
% P
% Gln:
17
0
0
34
17
34
0
0
17
0
0
0
0
0
0
% Q
% Arg:
9
0
0
9
0
0
9
9
0
0
0
9
0
0
0
% R
% Ser:
0
25
9
0
9
17
0
25
0
0
9
0
34
34
34
% S
% Thr:
0
0
0
25
9
0
9
17
0
0
0
0
17
34
25
% T
% Val:
9
0
9
9
0
0
0
9
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _