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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS2
All Species:
22.12
Human Site:
S416
Identified Species:
44.24
UniProt:
Q86VP3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VP3
NP_001094383.1
889
97702
S416
G
R
I
T
K
T
E
S
L
V
I
P
S
T
R
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
Q491
K
S
S
K
T
D
L
Q
G
S
A
S
P
S
K
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
Q490
K
S
S
K
T
D
L
Q
G
S
A
S
P
S
K
Dog
Lupus familis
XP_548006
1096
119669
S621
G
R
I
T
K
T
E
S
L
V
I
P
S
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3V3Q7
862
94918
S387
G
R
I
I
K
T
E
S
L
V
I
P
S
T
R
Rat
Rattus norvegicus
O88588
961
104682
Q489
K
S
S
K
A
D
L
Q
G
S
A
S
P
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
D70
S
E
Q
E
A
S
D
D
A
V
Q
G
Q
W
S
Chicken
Gallus gallus
XP_422219
894
99206
S421
G
K
I
T
K
T
E
S
L
I
I
P
S
T
R
Frog
Xenopus laevis
NP_001124414
878
97767
S404
G
K
I
T
K
T
E
S
L
I
I
P
S
T
R
Zebra Danio
Brachydanio rerio
NP_001116223
878
97631
S407
G
R
M
T
K
T
E
S
L
I
I
P
S
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120982
812
90475
P365
P
N
Y
V
T
G
S
P
P
K
S
E
Q
H
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
N270
Y
D
D
L
S
L
I
N
Y
S
D
S
G
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.7
53.7
73.4
N.A.
91.1
54.6
N.A.
46.9
85.6
82.1
74.5
N.A.
N.A.
38.9
N.A.
31.8
Protein Similarity:
100
68.3
67.4
76.3
N.A.
93.3
68.5
N.A.
52.4
91.2
89.8
84.6
N.A.
N.A.
57.5
N.A.
47.5
P-Site Identity:
100
0
0
100
N.A.
93.3
0
N.A.
6.6
86.6
86.6
80
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
13.3
13.3
100
N.A.
93.3
13.3
N.A.
20
100
100
93.3
N.A.
N.A.
0
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
9
0
25
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
25
9
9
0
0
9
0
0
0
9
% D
% Glu:
0
9
0
9
0
0
50
0
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
0
0
0
9
0
0
25
0
0
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
42
9
0
0
9
0
0
25
50
0
0
0
0
% I
% Lys:
25
17
0
25
50
0
0
0
0
9
0
0
0
0
25
% K
% Leu:
0
0
0
9
0
9
25
0
50
0
0
0
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
9
0
0
0
0
0
9
9
% N
% Pro:
9
0
0
0
0
0
0
9
9
0
0
50
25
9
0
% P
% Gln:
0
0
9
0
0
0
0
25
0
0
9
0
17
0
0
% Q
% Arg:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
50
% R
% Ser:
9
25
25
0
9
9
9
50
0
34
9
34
50
25
9
% S
% Thr:
0
0
0
42
25
50
0
0
0
0
0
0
0
42
0
% T
% Val:
0
0
0
9
0
0
0
0
0
34
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
9
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _