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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS2
All Species:
20.61
Human Site:
S421
Identified Species:
41.21
UniProt:
Q86VP3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VP3
NP_001094383.1
889
97702
S421
T
E
S
L
V
I
P
S
T
R
S
E
G
K
Q
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
P496
D
L
Q
G
S
A
S
P
S
K
V
E
G
V
H
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
P495
D
L
Q
G
S
A
S
P
S
K
V
E
G
V
H
Dog
Lupus familis
XP_548006
1096
119669
S626
T
E
S
L
V
I
P
S
T
R
S
E
G
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3V3Q7
862
94918
S392
T
E
S
L
V
I
P
S
T
R
S
E
S
K
P
Rat
Rattus norvegicus
O88588
961
104682
P494
D
L
Q
G
S
A
S
P
S
K
V
E
G
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
Q75
S
D
D
A
V
Q
G
Q
W
S
D
D
D
D
D
Chicken
Gallus gallus
XP_422219
894
99206
S426
T
E
S
L
I
I
P
S
T
R
S
E
G
K
Q
Frog
Xenopus laevis
NP_001124414
878
97767
S409
T
E
S
L
I
I
P
S
T
R
L
E
G
K
Q
Zebra Danio
Brachydanio rerio
NP_001116223
878
97631
S412
T
E
S
L
I
I
P
S
N
R
V
E
P
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120982
812
90475
Q370
G
S
P
P
K
S
E
Q
H
N
K
T
E
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
G275
L
I
N
Y
S
D
S
G
P
D
M
D
P
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.7
53.7
73.4
N.A.
91.1
54.6
N.A.
46.9
85.6
82.1
74.5
N.A.
N.A.
38.9
N.A.
31.8
Protein Similarity:
100
68.3
67.4
76.3
N.A.
93.3
68.5
N.A.
52.4
91.2
89.8
84.6
N.A.
N.A.
57.5
N.A.
47.5
P-Site Identity:
100
13.3
13.3
100
N.A.
86.6
13.3
N.A.
6.6
93.3
86.6
66.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
26.6
26.6
100
N.A.
86.6
26.6
N.A.
26.6
100
93.3
73.3
N.A.
N.A.
0
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
25
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
9
9
0
0
9
0
0
0
9
9
17
9
17
9
% D
% Glu:
0
50
0
0
0
0
9
0
0
0
0
75
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
25
0
0
9
9
0
0
0
0
59
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
25
% H
% Ile:
0
9
0
0
25
50
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
25
9
0
0
50
0
% K
% Leu:
9
25
0
50
0
0
0
0
0
0
9
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
9
9
0
0
0
0
0
% N
% Pro:
0
0
9
9
0
0
50
25
9
0
0
0
17
0
9
% P
% Gln:
0
0
25
0
0
9
0
17
0
0
0
0
0
0
34
% Q
% Arg:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% R
% Ser:
9
9
50
0
34
9
34
50
25
9
34
0
9
9
9
% S
% Thr:
50
0
0
0
0
0
0
0
42
0
0
9
0
9
0
% T
% Val:
0
0
0
0
34
0
0
0
0
0
34
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _