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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS2
All Species:
12.12
Human Site:
S691
Identified Species:
24.24
UniProt:
Q86VP3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VP3
NP_001094383.1
889
97702
S691
V
E
P
S
S
A
T
S
G
D
S
D
D
A
A
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
A764
V
E
D
S
P
S
T
A
G
D
G
D
D
S
P
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
A763
V
E
D
S
P
S
T
A
G
D
G
D
D
S
P
Dog
Lupus familis
XP_548006
1096
119669
P898
L
P
N
C
L
I
L
P
G
D
S
D
D
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3V3Q7
862
94918
D664
P
S
S
A
T
S
G
D
S
D
D
A
A
P
S
Rat
Rattus norvegicus
O88588
961
104682
A762
V
E
D
S
P
S
T
A
G
D
G
D
D
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
N333
K
T
V
Y
D
Q
L
N
H
I
L
I
S
D
D
Chicken
Gallus gallus
XP_422219
894
99206
S696
V
E
Q
S
S
A
T
S
G
D
S
D
D
A
A
Frog
Xenopus laevis
NP_001124414
878
97767
S679
V
E
Q
S
S
A
T
S
G
D
S
D
D
A
A
Zebra Danio
Brachydanio rerio
NP_001116223
878
97631
S683
V
E
Q
T
S
V
A
S
G
D
S
D
D
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120982
812
90475
L628
S
S
S
A
S
V
D
L
E
E
S
N
V
T
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
I533
R
V
L
S
P
I
K
I
G
V
C
G
S
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.7
53.7
73.4
N.A.
91.1
54.6
N.A.
46.9
85.6
82.1
74.5
N.A.
N.A.
38.9
N.A.
31.8
Protein Similarity:
100
68.3
67.4
76.3
N.A.
93.3
68.5
N.A.
52.4
91.2
89.8
84.6
N.A.
N.A.
57.5
N.A.
47.5
P-Site Identity:
100
53.3
53.3
46.6
N.A.
6.6
53.3
N.A.
0
93.3
93.3
73.3
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
73.3
73.3
53.3
N.A.
33.3
73.3
N.A.
6.6
93.3
93.3
80
N.A.
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
25
9
25
0
0
0
9
9
42
42
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
25
0
9
0
9
9
0
75
9
67
67
17
9
% D
% Glu:
0
59
0
0
0
0
0
0
9
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
75
0
25
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
17
0
9
0
9
0
9
0
0
0
% I
% Lys:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
9
0
9
0
17
9
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
0
0
0
9
0
0
0
9
0
0
0
% N
% Pro:
9
9
9
0
34
0
0
9
0
0
0
0
0
9
25
% P
% Gln:
0
0
25
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
17
17
59
42
34
0
34
9
0
50
0
17
25
17
% S
% Thr:
0
9
0
9
9
0
50
0
0
0
0
0
0
9
0
% T
% Val:
59
9
9
0
0
17
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _