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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PACS2 All Species: 21.82
Human Site: S707 Identified Species: 43.64
UniProt: Q86VP3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VP3 NP_001094383.1 889 97702 S707 S G S G T L S S T P P S A S P
Chimpanzee Pan troglodytes XP_001170787 963 104910 T780 V S L T V P S T S P P S S S G
Rhesus Macaque Macaca mulatta XP_001111390 962 105061 T779 V S L T V P S T S P P S S S G
Dog Lupus familis XP_548006 1096 119669 S914 S G S S M L S S T P P S T S P
Cat Felis silvestris
Mouse Mus musculus Q3V3Q7 862 94918 P680 S S I L S S T P P S A S T S P
Rat Rattus norvegicus O88588 961 104682 T778 V S L T V P S T S P P S S S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517191 517 58756 V349 L P E N I I L V N T S D W Q G
Chicken Gallus gallus XP_422219 894 99206 S712 S S S S V L S S T P P S V S P
Frog Xenopus laevis NP_001124414 878 97767 S695 S G S T V L S S T P P S V S P
Zebra Danio Brachydanio rerio NP_001116223 878 97631 S699 V G S A L M S S T P P A Q I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120982 812 90475 P644 G S P P S L P P P G L P I P L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796424 717 79113 Y549 I G S V L K P Y V E Q F S A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.7 53.7 73.4 N.A. 91.1 54.6 N.A. 46.9 85.6 82.1 74.5 N.A. N.A. 38.9 N.A. 31.8
Protein Similarity: 100 68.3 67.4 76.3 N.A. 93.3 68.5 N.A. 52.4 91.2 89.8 84.6 N.A. N.A. 57.5 N.A. 47.5
P-Site Identity: 100 33.3 33.3 80 N.A. 26.6 33.3 N.A. 0 73.3 80 46.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 53.3 53.3 80 N.A. 40 53.3 N.A. 6.6 73.3 80 60 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 0 9 9 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 9 42 0 9 0 0 0 0 0 9 0 0 0 0 34 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 9 0 9 9 0 0 0 0 0 0 9 9 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % K
% Leu: 9 0 25 9 17 42 9 0 0 0 9 0 0 0 9 % L
% Met: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 9 9 9 0 25 17 17 17 67 67 9 0 9 42 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 9 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 42 50 50 17 17 9 67 42 25 9 9 67 34 67 9 % S
% Thr: 0 0 0 34 9 0 9 25 42 9 0 0 17 0 0 % T
% Val: 34 0 0 9 42 0 0 9 9 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _