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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS2
All Species:
33.03
Human Site:
T125
Identified Species:
66.06
UniProt:
Q86VP3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VP3
NP_001094383.1
889
97702
T125
R
K
R
Y
K
N
R
T
I
L
G
Y
K
T
L
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
T204
R
K
R
Y
K
N
R
T
I
L
G
Y
K
T
L
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
T203
R
K
R
Y
K
N
R
T
I
L
G
Y
K
T
L
Dog
Lupus familis
XP_548006
1096
119669
T330
R
K
R
Y
K
N
R
T
I
L
G
Y
K
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3V3Q7
862
94918
N108
T
L
A
A
G
S
I
N
M
A
E
V
M
Q
H
Rat
Rattus norvegicus
O88588
961
104682
T202
R
K
R
Y
K
N
R
T
I
L
G
Y
K
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
Chicken
Gallus gallus
XP_422219
894
99206
T128
R
K
R
Y
K
N
R
T
I
L
G
Y
K
T
L
Frog
Xenopus laevis
NP_001124414
878
97767
T122
R
K
R
Y
K
N
R
T
I
L
G
Y
K
T
L
Zebra Danio
Brachydanio rerio
NP_001116223
878
97631
T125
R
K
R
Y
K
N
R
T
I
L
G
Y
K
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120982
812
90475
Y95
E
L
Q
F
A
L
Q
Y
P
H
F
L
K
R
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.7
53.7
73.4
N.A.
91.1
54.6
N.A.
46.9
85.6
82.1
74.5
N.A.
N.A.
38.9
N.A.
31.8
Protein Similarity:
100
68.3
67.4
76.3
N.A.
93.3
68.5
N.A.
52.4
91.2
89.8
84.6
N.A.
N.A.
57.5
N.A.
47.5
P-Site Identity:
100
100
100
100
N.A.
0
100
N.A.
0
100
100
100
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
13.3
100
N.A.
0
100
100
100
N.A.
N.A.
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
67
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
9
0
67
0
0
0
0
0
0
% I
% Lys:
0
67
0
0
67
0
0
0
0
0
0
0
75
0
0
% K
% Leu:
0
17
0
0
0
9
0
0
0
67
0
9
0
0
67
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
67
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
9
0
0
0
0
0
0
9
0
% Q
% Arg:
67
0
67
0
0
0
67
0
0
0
0
0
0
9
0
% R
% Ser:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
67
0
0
0
0
0
67
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
67
0
0
0
9
0
0
0
67
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _