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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS2
All Species:
30.91
Human Site:
Y605
Identified Species:
61.82
UniProt:
Q86VP3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VP3
NP_001094383.1
889
97702
Y605
L
G
S
V
D
Y
R
Y
N
N
F
F
Q
D
L
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
Y680
L
G
S
V
D
S
K
Y
S
S
S
F
L
D
S
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
Y679
L
G
S
V
D
S
K
Y
S
S
S
F
L
D
S
Dog
Lupus familis
XP_548006
1096
119669
Y810
L
G
S
V
D
Y
R
Y
N
N
F
F
Q
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3V3Q7
862
94918
Y576
L
G
S
V
D
Y
R
Y
N
N
F
F
Q
D
L
Rat
Rattus norvegicus
O88588
961
104682
Y678
L
G
S
V
D
S
R
Y
S
S
T
F
L
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
E258
S
T
L
D
V
F
I
E
K
L
P
P
S
G
K
Chicken
Gallus gallus
XP_422219
894
99206
Y610
L
G
S
V
D
Y
R
Y
N
N
F
F
Q
D
V
Frog
Xenopus laevis
NP_001124414
878
97767
Y593
L
G
S
V
D
Y
K
Y
N
N
L
F
Q
D
P
Zebra Danio
Brachydanio rerio
NP_001116223
878
97631
Y596
L
A
S
I
D
Y
R
Y
N
S
L
F
L
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120982
812
90475
G553
A
K
Y
S
M
L
F
G
D
E
W
K
E
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
Q458
P
K
L
P
I
T
E
Q
L
S
E
L
W
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.7
53.7
73.4
N.A.
91.1
54.6
N.A.
46.9
85.6
82.1
74.5
N.A.
N.A.
38.9
N.A.
31.8
Protein Similarity:
100
68.3
67.4
76.3
N.A.
93.3
68.5
N.A.
52.4
91.2
89.8
84.6
N.A.
N.A.
57.5
N.A.
47.5
P-Site Identity:
100
53.3
53.3
100
N.A.
100
60
N.A.
0
93.3
80
60
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
73.3
73.3
100
N.A.
100
73.3
N.A.
6.6
100
86.6
73.3
N.A.
N.A.
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
75
0
0
0
9
0
0
0
0
75
0
% D
% Glu:
0
0
0
0
0
0
9
9
0
9
9
0
9
0
0
% E
% Phe:
0
0
0
0
0
9
9
0
0
0
34
75
0
0
0
% F
% Gly:
0
67
0
0
0
0
0
9
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
0
0
0
25
0
9
0
0
9
0
0
9
% K
% Leu:
75
0
17
0
0
9
0
0
9
9
17
9
34
17
34
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
50
42
0
0
0
0
0
% N
% Pro:
9
0
0
9
0
0
0
0
0
0
9
9
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
42
0
0
% Q
% Arg:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
75
9
0
25
0
0
25
42
17
0
9
0
34
% S
% Thr:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
9
% T
% Val:
0
0
0
67
9
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% W
% Tyr:
0
0
9
0
0
50
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _