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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAND1
All Species:
45.15
Human Site:
S489
Identified Species:
82.78
UniProt:
Q86VP6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VP6
NP_060918.2
1230
136376
S489
F
S
L
N
D
K
S
S
S
S
N
L
K
I
D
Chimpanzee
Pan troglodytes
XP_509204
1350
150071
S609
F
S
L
N
D
K
S
S
S
S
N
L
K
I
D
Rhesus Macaque
Macaca mulatta
XP_001106780
1351
150139
S610
F
S
L
N
D
K
S
S
S
S
N
L
K
I
D
Dog
Lupus familis
XP_531667
1206
133582
S465
F
S
L
N
D
K
S
S
S
S
N
L
K
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQ38
1230
136313
S489
F
S
L
N
D
K
S
S
S
S
N
L
K
I
D
Rat
Rattus norvegicus
P97536
1230
136343
S489
F
S
L
N
D
K
S
S
S
S
N
L
K
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511066
1243
137773
S502
F
S
L
N
D
K
S
S
S
S
N
L
K
I
D
Chicken
Gallus gallus
XP_416078
1191
131738
D457
S
S
S
N
L
K
I
D
A
L
S
C
L
Y
V
Frog
Xenopus laevis
NP_001085373
1230
136368
S489
F
S
L
N
D
K
S
S
S
S
N
L
K
I
D
Zebra Danio
Brachydanio rerio
NP_998650
1230
136018
S489
F
S
L
N
D
K
S
S
S
S
N
L
K
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609389
1248
139337
S485
Y
S
L
N
D
K
S
S
T
S
N
M
K
I
E
Honey Bee
Apis mellifera
XP_393409
1235
138752
S490
Y
S
L
G
D
K
N
S
S
S
N
M
K
I
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791290
981
108569
P286
E
S
F
V
R
R
C
P
K
E
V
S
P
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
91
97.9
N.A.
99.4
99.7
N.A.
96.4
94.2
97.1
93.8
N.A.
58.8
68
N.A.
57.8
Protein Similarity:
100
91.1
91
98
N.A.
99.7
99.8
N.A.
97.7
95.8
98.5
97
N.A.
75.8
82.4
N.A.
69.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
20
100
100
N.A.
73.3
73.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
33.3
100
100
N.A.
100
93.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
85
0
0
8
0
0
0
0
0
0
77
% D
% Glu:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% E
% Phe:
70
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
85
0
% I
% Lys:
0
0
0
0
0
93
0
0
8
0
0
0
85
0
0
% K
% Leu:
0
0
85
0
8
0
0
0
0
8
0
70
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% M
% Asn:
0
0
0
85
0
0
8
0
0
0
85
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
100
8
0
0
0
77
85
77
85
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _