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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAND1
All Species:
40.91
Human Site:
Y291
Identified Species:
75
UniProt:
Q86VP6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VP6
NP_060918.2
1230
136376
Y291
R
R
C
P
K
E
V
Y
P
H
V
S
T
I
I
Chimpanzee
Pan troglodytes
XP_509204
1350
150071
Y411
R
R
C
P
K
E
V
Y
P
H
V
S
T
I
I
Rhesus Macaque
Macaca mulatta
XP_001106780
1351
150139
Y412
R
R
C
P
K
E
V
Y
P
H
V
S
T
I
I
Dog
Lupus familis
XP_531667
1206
133582
Y267
R
R
C
P
K
E
V
Y
P
H
V
S
T
I
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQ38
1230
136313
Y291
R
R
C
P
K
E
V
Y
P
H
V
S
T
I
I
Rat
Rattus norvegicus
P97536
1230
136343
Y291
R
R
C
P
K
E
V
Y
P
H
V
S
T
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511066
1243
137773
Y304
R
R
C
P
K
E
V
Y
P
H
V
S
T
I
I
Chicken
Gallus gallus
XP_416078
1191
131738
T267
N
I
C
L
K
Y
L
T
Y
D
P
N
Y
N
Y
Frog
Xenopus laevis
NP_001085373
1230
136368
Y291
R
R
C
P
K
E
V
Y
P
H
V
S
T
I
I
Zebra Danio
Brachydanio rerio
NP_998650
1230
136018
Y291
R
R
C
P
K
E
V
Y
P
H
V
P
T
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609389
1248
139337
N289
M
R
C
P
D
A
I
N
P
H
I
P
M
I
L
Honey Bee
Apis mellifera
XP_393409
1235
138752
T289
Y
R
C
P
K
E
I
T
P
H
I
N
K
I
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791290
981
108569
E100
N
N
M
L
S
D
K
E
Q
L
R
D
I
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
91
97.9
N.A.
99.4
99.7
N.A.
96.4
94.2
97.1
93.8
N.A.
58.8
68
N.A.
57.8
Protein Similarity:
100
91.1
91
98
N.A.
99.7
99.8
N.A.
97.7
95.8
98.5
97
N.A.
75.8
82.4
N.A.
69.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
100
86.6
N.A.
40
60
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
26.6
100
93.3
N.A.
60
80
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
93
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
0
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
77
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
85
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
16
0
0
0
16
0
8
77
77
% I
% Lys:
0
0
0
0
85
0
8
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
16
0
0
8
0
0
8
0
0
0
0
8
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
16
8
0
0
0
0
0
8
0
0
0
16
0
8
0
% N
% Pro:
0
0
0
85
0
0
0
0
85
0
8
16
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
70
85
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
0
0
0
0
62
0
8
8
% S
% Thr:
0
0
0
0
0
0
0
16
0
0
0
0
70
0
0
% T
% Val:
0
0
0
0
0
0
70
0
0
0
70
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
70
8
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _