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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCA5
All Species:
33.94
Human Site:
S252
Identified Species:
67.88
UniProt:
Q86VQ0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VQ0
NP_001116241.1
697
80554
S252
N
L
E
L
S
T
N
S
F
Q
R
Q
L
L
A
Chimpanzee
Pan troglodytes
XP_527439
697
80636
S252
N
L
E
L
S
T
N
S
F
Q
R
Q
L
L
A
Rhesus Macaque
Macaca mulatta
XP_001113835
697
80763
S252
N
L
E
L
S
T
N
S
F
Q
R
Q
L
L
A
Dog
Lupus familis
XP_539014
700
80916
S255
N
L
E
L
S
T
N
S
F
Q
R
Q
L
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80ST9
704
80143
S255
N
L
E
L
S
T
N
S
F
Q
R
Q
L
L
A
Rat
Rattus norvegicus
Q5U2Y9
727
82591
S256
N
L
E
L
S
T
N
S
F
Q
R
Q
L
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520366
909
100353
S372
N
L
E
L
S
N
S
S
F
Q
R
Q
L
H
S
Chicken
Gallus gallus
XP_419870
683
79593
S255
N
L
E
L
S
G
S
S
F
Q
R
E
L
Q
L
Frog
Xenopus laevis
Q9PW73
1335
154049
Q606
Q
I
E
H
L
Q
L
Q
L
E
M
K
N
L
H
Zebra Danio
Brachydanio rerio
XP_001919911
754
87027
S306
N
M
E
L
S
S
G
S
F
Q
R
Q
L
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730235
569
63849
K188
Y
S
Q
L
N
K
D
K
N
L
D
E
R
Q
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788900
765
88095
N262
H
V
E
N
M
K
K
N
V
R
H
D
S
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.2
83.4
N.A.
69.5
67.4
N.A.
35.8
47.4
20.3
33.2
N.A.
21.2
N.A.
N.A.
23.2
Protein Similarity:
100
99.1
96.8
89.8
N.A.
81.9
78.2
N.A.
50.3
64.8
33.4
53.4
N.A.
40
N.A.
N.A.
41.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
73.3
66.6
13.3
66.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
80
33.3
80
N.A.
33.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
9
9
0
0
0
% D
% Glu:
0
0
92
0
0
0
0
0
0
9
0
17
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
9
0
0
0
0
0
0
9
0
0
9
9
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
17
9
9
0
0
0
9
0
0
9
% K
% Leu:
0
67
0
84
9
0
9
0
9
9
0
0
75
59
9
% L
% Met:
0
9
0
0
9
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
75
0
0
9
9
9
50
9
9
0
0
0
9
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
9
0
0
9
0
9
0
75
0
67
0
17
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
75
0
9
0
0
% R
% Ser:
0
9
0
0
75
9
17
75
0
0
0
0
9
0
9
% S
% Thr:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% T
% Val:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _