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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCA5
All Species:
18.18
Human Site:
S512
Identified Species:
36.36
UniProt:
Q86VQ0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VQ0
NP_001116241.1
697
80554
S512
S
P
K
T
Y
R
F
S
E
S
S
E
R
L
F
Chimpanzee
Pan troglodytes
XP_527439
697
80636
S512
S
P
K
T
Y
R
F
S
E
S
S
E
R
L
F
Rhesus Macaque
Macaca mulatta
XP_001113835
697
80763
S512
S
P
K
T
Y
R
L
S
E
S
S
E
R
L
F
Dog
Lupus familis
XP_539014
700
80916
S515
T
P
K
M
Y
M
S
S
E
S
S
E
R
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q80ST9
704
80143
S517
F
P
E
S
L
D
R
S
F
N
G
Q
H
L
Q
Rat
Rattus norvegicus
Q5U2Y9
727
82591
S512
S
L
R
P
Y
T
F
S
E
S
L
D
R
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520366
909
100353
H731
R
S
G
S
P
E
K
H
G
K
A
P
G
L
S
Chicken
Gallus gallus
XP_419870
683
79593
K506
K
S
D
S
P
E
K
K
E
R
N
G
Q
F
F
Frog
Xenopus laevis
Q9PW73
1335
154049
S978
Q
L
T
Q
L
D
M
S
I
R
G
H
K
G
E
Zebra Danio
Brachydanio rerio
XP_001919911
754
87027
I534
Q
K
V
R
N
R
E
I
Q
D
Y
N
Q
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730235
569
63849
K397
A
E
T
K
P
K
Q
K
P
L
E
Y
E
Y
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788900
765
88095
N487
A
P
K
T
P
I
F
N
G
A
S
S
D
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.2
83.4
N.A.
69.5
67.4
N.A.
35.8
47.4
20.3
33.2
N.A.
21.2
N.A.
N.A.
23.2
Protein Similarity:
100
99.1
96.8
89.8
N.A.
81.9
78.2
N.A.
50.3
64.8
33.4
53.4
N.A.
40
N.A.
N.A.
41.7
P-Site Identity:
100
100
93.3
60
N.A.
20
53.3
N.A.
6.6
13.3
6.6
6.6
N.A.
0
N.A.
N.A.
33.3
P-Site Similarity:
100
100
93.3
80
N.A.
46.6
66.6
N.A.
20
33.3
13.3
20
N.A.
13.3
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
17
0
0
0
9
0
9
9
0
0
% D
% Glu:
0
9
9
0
0
17
9
0
50
0
9
34
9
17
25
% E
% Phe:
9
0
0
0
0
0
34
0
9
0
0
0
0
9
42
% F
% Gly:
0
0
9
0
0
0
0
0
17
0
17
9
9
9
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
9
9
0
0
% H
% Ile:
0
0
0
0
0
9
0
9
9
0
0
0
0
9
0
% I
% Lys:
9
9
42
9
0
9
17
17
0
9
0
0
9
0
0
% K
% Leu:
0
17
0
0
17
0
9
0
0
9
9
0
0
42
0
% L
% Met:
0
0
0
9
0
9
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
9
0
9
9
9
0
0
0
% N
% Pro:
0
50
0
9
34
0
0
0
9
0
0
9
0
0
0
% P
% Gln:
17
0
0
9
0
0
9
0
9
0
0
9
17
0
9
% Q
% Arg:
9
0
9
9
0
34
9
0
0
17
0
0
42
0
9
% R
% Ser:
34
17
0
25
0
0
9
59
0
42
42
9
0
9
9
% S
% Thr:
9
0
17
34
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
42
0
0
0
0
0
9
9
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _