KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCA5
All Species:
9.39
Human Site:
S539
Identified Species:
18.79
UniProt:
Q86VQ0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VQ0
NP_001116241.1
697
80554
S539
P
K
G
E
G
Q
N
S
G
N
V
R
S
P
A
Chimpanzee
Pan troglodytes
XP_527439
697
80636
S539
P
K
G
E
G
Q
N
S
G
N
V
R
S
P
A
Rhesus Macaque
Macaca mulatta
XP_001113835
697
80763
S539
P
K
R
E
G
Q
N
S
G
N
V
R
S
P
A
Dog
Lupus familis
XP_539014
700
80916
L542
T
K
G
D
V
Q
N
L
G
N
I
R
S
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80ST9
704
80143
P544
S
P
G
P
I
R
S
P
G
Q
I
R
S
P
A
Rat
Rattus norvegicus
Q5U2Y9
727
82591
P539
P
R
D
E
G
Q
S
P
G
L
I
R
S
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520366
909
100353
P758
L
R
D
G
G
Q
G
P
R
S
L
R
G
S
D
Chicken
Gallus gallus
XP_419870
683
79593
T533
E
D
S
Q
E
D
A
T
R
A
H
G
Q
K
Q
Frog
Xenopus laevis
Q9PW73
1335
154049
R1005
E
K
A
E
L
E
A
R
D
H
I
K
E
I
S
Zebra Danio
Brachydanio rerio
XP_001919911
754
87027
I561
A
K
M
R
E
I
D
I
Q
T
Q
G
Q
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730235
569
63849
K424
D
A
Y
G
M
M
S
K
M
C
E
G
E
E
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788900
765
88095
G514
A
P
Y
S
R
P
K
G
A
P
P
P
S
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.2
83.4
N.A.
69.5
67.4
N.A.
35.8
47.4
20.3
33.2
N.A.
21.2
N.A.
N.A.
23.2
Protein Similarity:
100
99.1
96.8
89.8
N.A.
81.9
78.2
N.A.
50.3
64.8
33.4
53.4
N.A.
40
N.A.
N.A.
41.7
P-Site Identity:
100
100
93.3
60
N.A.
40
60
N.A.
20
0
13.3
6.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
73.3
N.A.
60
80
N.A.
40
13.3
46.6
20
N.A.
6.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
9
0
0
0
17
0
9
9
0
0
0
0
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
9
9
17
9
0
9
9
0
9
0
0
0
0
9
17
% D
% Glu:
17
0
0
42
17
9
0
0
0
0
9
0
17
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
34
17
42
0
9
9
50
0
0
25
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
0
9
0
0
34
0
0
9
0
% I
% Lys:
0
50
0
0
0
0
9
9
0
0
0
9
0
9
0
% K
% Leu:
9
0
0
0
9
0
0
9
0
9
9
0
0
0
0
% L
% Met:
0
0
9
0
9
9
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
34
0
0
34
0
0
0
0
9
% N
% Pro:
34
17
0
9
0
9
0
25
0
9
9
9
0
50
9
% P
% Gln:
0
0
0
9
0
50
0
0
9
9
9
0
17
0
9
% Q
% Arg:
0
17
9
9
9
9
0
9
17
0
0
59
0
0
0
% R
% Ser:
9
0
9
9
0
0
25
25
0
9
0
0
59
17
17
% S
% Thr:
9
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _