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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCA5
All Species:
18.48
Human Site:
S583
Identified Species:
36.97
UniProt:
Q86VQ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VQ0
NP_001116241.1
697
80554
S583
F
L
D
F
Q
R
N
S
M
E
K
L
S
K
D
Chimpanzee
Pan troglodytes
XP_527439
697
80636
S583
F
L
D
F
Q
R
N
S
M
E
K
L
S
K
D
Rhesus Macaque
Macaca mulatta
XP_001113835
697
80763
S583
F
L
D
F
Q
R
N
S
M
E
K
L
S
K
D
Dog
Lupus familis
XP_539014
700
80916
N586
L
L
D
V
Q
R
N
N
I
E
K
L
S
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80ST9
704
80143
S588
L
L
D
F
Q
S
N
S
S
E
S
P
S
K
D
Rat
Rattus norvegicus
Q5U2Y9
727
82591
M583
L
L
D
F
Q
S
N
M
S
E
G
L
S
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520366
909
100353
G802
F
P
D
P
E
S
S
G
A
A
R
S
R
P
G
Chicken
Gallus gallus
XP_419870
683
79593
S577
W
L
N
P
K
G
D
S
L
E
E
N
M
K
E
Frog
Xenopus laevis
Q9PW73
1335
154049
S1049
L
K
K
D
I
E
R
S
H
Q
T
V
T
D
M
Zebra Danio
Brachydanio rerio
XP_001919911
754
87027
T605
E
P
D
E
N
I
N
T
F
S
S
G
R
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730235
569
63849
Y468
L
E
E
S
M
E
E
Y
D
G
T
D
G
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788900
765
88095
E558
Q
R
K
K
Q
K
E
E
S
E
R
L
A
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.2
83.4
N.A.
69.5
67.4
N.A.
35.8
47.4
20.3
33.2
N.A.
21.2
N.A.
N.A.
23.2
Protein Similarity:
100
99.1
96.8
89.8
N.A.
81.9
78.2
N.A.
50.3
64.8
33.4
53.4
N.A.
40
N.A.
N.A.
41.7
P-Site Identity:
100
100
100
73.3
N.A.
66.6
66.6
N.A.
13.3
26.6
6.6
13.3
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
66.6
N.A.
33.3
73.3
26.6
26.6
N.A.
13.3
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
9
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
67
9
0
0
9
0
9
0
0
9
0
9
50
% D
% Glu:
9
9
9
9
9
17
17
9
0
67
9
0
0
9
17
% E
% Phe:
34
0
0
42
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
9
0
9
9
9
9
0
17
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
9
17
9
9
9
0
0
0
0
34
0
0
59
0
% K
% Leu:
42
59
0
0
0
0
0
0
9
0
0
50
0
0
0
% L
% Met:
0
0
0
0
9
0
0
9
25
0
0
0
9
0
9
% M
% Asn:
0
0
9
0
9
0
59
9
0
0
0
9
0
0
0
% N
% Pro:
0
17
0
17
0
0
0
0
0
0
0
9
0
9
0
% P
% Gln:
9
0
0
0
59
0
0
0
0
9
0
0
0
9
9
% Q
% Arg:
0
9
0
0
0
34
9
0
0
0
17
0
17
9
0
% R
% Ser:
0
0
0
9
0
25
9
50
25
9
17
9
50
0
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
17
0
9
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _