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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCA5 All Species: 19.39
Human Site: T365 Identified Species: 38.79
UniProt: Q86VQ0 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VQ0 NP_001116241.1 697 80554 T365 W E E P G H L T L D L Q S Q K
Chimpanzee Pan troglodytes XP_527439 697 80636 T365 W E E P G H L T L D L Q S Q K
Rhesus Macaque Macaca mulatta XP_001113835 697 80763 T365 W E E P E H L T L D L Q S Q K
Dog Lupus familis XP_539014 700 80916 T368 W E K P E R L T L D L E F Q E
Cat Felis silvestris
Mouse Mus musculus Q80ST9 704 80143 S367 W D E P E Y L S S Y L E Y Q D
Rat Rattus norvegicus Q5U2Y9 727 82591 P368 W D G S E Y L P S Y L E Y Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520366 909 100353 G515 R G N H E P S G G V N K S R Q
Chicken Gallus gallus XP_419870 683 79593 R369 K K E R I L S R I E K E P Q N
Frog Xenopus laevis Q9PW73 1335 154049 Q725 N E I K L R T Q S L Q E T S E
Zebra Danio Brachydanio rerio XP_001919911 754 87027 K417 T D D Y L S L K Q D Q Q S R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730235 569 63849 S296 F Y D F E K D S A E D K S G P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788900 765 88095 T385 K P E E K K V T P R I E E K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.2 83.4 N.A. 69.5 67.4 N.A. 35.8 47.4 20.3 33.2 N.A. 21.2 N.A. N.A. 23.2
Protein Similarity: 100 99.1 96.8 89.8 N.A. 81.9 78.2 N.A. 50.3 64.8 33.4 53.4 N.A. 40 N.A. N.A. 41.7
P-Site Identity: 100 100 93.3 60 N.A. 40 26.6 N.A. 6.6 13.3 6.6 26.6 N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 100 93.3 80 N.A. 66.6 53.3 N.A. 26.6 40 26.6 53.3 N.A. 40 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 25 17 0 0 0 9 0 0 42 9 0 0 0 9 % D
% Glu: 0 42 50 9 50 0 0 0 0 17 0 50 9 0 34 % E
% Phe: 9 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 9 9 0 17 0 0 9 9 0 0 0 0 9 0 % G
% His: 0 0 0 9 0 25 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 9 0 0 0 9 0 9 0 0 0 0 % I
% Lys: 17 9 9 9 9 17 0 9 0 0 9 17 0 9 34 % K
% Leu: 0 0 0 0 17 9 59 0 34 9 50 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 0 0 0 0 0 9 0 0 0 9 % N
% Pro: 0 9 0 42 0 9 0 9 9 0 0 0 9 0 9 % P
% Gln: 0 0 0 0 0 0 0 9 9 0 17 34 0 59 9 % Q
% Arg: 9 0 0 9 0 17 0 9 0 9 0 0 0 17 0 % R
% Ser: 0 0 0 9 0 9 17 17 25 0 0 0 50 9 0 % S
% Thr: 9 0 0 0 0 0 9 42 0 0 0 0 9 0 0 % T
% Val: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % V
% Trp: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 9 0 17 0 0 0 17 0 0 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _