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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCA5 All Species: 38.48
Human Site: Y298 Identified Species: 76.97
UniProt: Q86VQ0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VQ0 NP_001116241.1 697 80554 Y298 E L D I K N I Y S N R L P K S
Chimpanzee Pan troglodytes XP_527439 697 80636 Y298 E L D I K N I Y S N R L P K S
Rhesus Macaque Macaca mulatta XP_001113835 697 80763 Y298 E L D I K N I Y S N R L P K S
Dog Lupus familis XP_539014 700 80916 Y301 E L D I K N I Y S N R L P K S
Cat Felis silvestris
Mouse Mus musculus Q80ST9 704 80143 Y301 E L D I K N I Y A N R L P K S
Rat Rattus norvegicus Q5U2Y9 727 82591 Y302 E L D I K N I Y A N R L P K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520366 909 100353 Y419 E L D V K N I Y S N R L A K S
Chicken Gallus gallus XP_419870 683 79593 Y301 E L D A K N I Y A N R M L K V
Frog Xenopus laevis Q9PW73 1335 154049 N655 E L E I Q T K N T S A A M K S
Zebra Danio Brachydanio rerio XP_001919911 754 87027 Y352 E L D A R N I Y A N R M H K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730235 569 63849 Q231 E S K N I R Q Q L L N E Q R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788900 765 88095 Y308 E L D I R N I Y S H R V M K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.2 83.4 N.A. 69.5 67.4 N.A. 35.8 47.4 20.3 33.2 N.A. 21.2 N.A. N.A. 23.2
Protein Similarity: 100 99.1 96.8 89.8 N.A. 81.9 78.2 N.A. 50.3 64.8 33.4 53.4 N.A. 40 N.A. N.A. 41.7
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 66.6 33.3 60 N.A. 6.6 N.A. N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 80 60 86.6 N.A. 13.3 N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 0 0 0 0 34 0 9 9 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 84 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 100 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % H
% Ile: 0 0 0 67 9 0 84 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 9 0 67 0 9 0 0 0 0 0 0 92 9 % K
% Leu: 0 92 0 0 0 0 0 0 9 9 0 59 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 17 17 0 0 % M
% Asn: 0 0 0 9 0 84 0 9 0 75 9 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 9 % P
% Gln: 0 0 0 0 9 0 9 9 0 0 0 0 9 0 0 % Q
% Arg: 0 0 0 0 17 9 0 0 0 0 84 0 0 9 0 % R
% Ser: 0 9 0 0 0 0 0 0 50 9 0 0 0 0 67 % S
% Thr: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % T
% Val: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 84 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _