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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCA5
All Species:
21.52
Human Site:
Y354
Identified Species:
43.03
UniProt:
Q86VQ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VQ0
NP_001116241.1
697
80554
Y354
T
P
E
T
I
M
C
Y
E
N
K
W
E
E
P
Chimpanzee
Pan troglodytes
XP_527439
697
80636
Y354
T
P
E
T
I
M
C
Y
E
N
K
W
E
E
P
Rhesus Macaque
Macaca mulatta
XP_001113835
697
80763
Y354
T
P
E
T
I
M
C
Y
E
N
K
W
E
E
P
Dog
Lupus familis
XP_539014
700
80916
Y357
T
P
Q
T
V
M
C
Y
E
N
K
W
E
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80ST9
704
80143
Y356
T
A
Q
T
V
L
C
Y
E
N
R
W
D
E
P
Rat
Rattus norvegicus
Q5U2Y9
727
82591
Y357
T
A
Q
T
V
L
C
Y
E
N
R
W
D
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520366
909
100353
D504
R
P
A
L
S
S
V
D
V
R
G
R
G
N
H
Chicken
Gallus gallus
XP_419870
683
79593
D358
E
S
E
L
V
C
G
D
P
V
D
K
K
E
R
Frog
Xenopus laevis
Q9PW73
1335
154049
W714
K
T
K
S
E
E
L
W
C
L
Q
N
E
I
K
Zebra Danio
Brachydanio rerio
XP_001919911
754
87027
P406
A
L
T
N
N
L
P
P
D
D
Q
T
D
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730235
569
63849
E285
T
A
L
T
D
V
M
E
S
E
S
F
Y
D
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788900
765
88095
K374
R
P
P
K
P
E
V
K
P
E
V
K
P
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.2
83.4
N.A.
69.5
67.4
N.A.
35.8
47.4
20.3
33.2
N.A.
21.2
N.A.
N.A.
23.2
Protein Similarity:
100
99.1
96.8
89.8
N.A.
81.9
78.2
N.A.
50.3
64.8
33.4
53.4
N.A.
40
N.A.
N.A.
41.7
P-Site Identity:
100
100
100
80
N.A.
60
46.6
N.A.
6.6
13.3
6.6
0
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
80
N.A.
6.6
26.6
33.3
40
N.A.
33.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
50
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
17
9
9
9
0
25
17
0
% D
% Glu:
9
0
34
0
9
17
0
9
50
17
0
0
42
50
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
9
0
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
25
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
9
0
9
9
0
0
0
9
0
0
34
17
9
9
9
% K
% Leu:
0
9
9
17
0
25
9
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
34
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
9
0
0
0
0
50
0
9
0
9
0
% N
% Pro:
0
50
9
0
9
0
9
9
17
0
0
0
9
0
42
% P
% Gln:
0
0
25
0
0
0
0
0
0
0
17
0
0
0
0
% Q
% Arg:
17
0
0
0
0
0
0
0
0
9
17
9
0
0
9
% R
% Ser:
0
9
0
9
9
9
0
0
9
0
9
0
0
0
9
% S
% Thr:
59
9
9
59
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
0
0
34
9
17
0
9
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
50
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _