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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCA5
All Species:
13.94
Human Site:
Y441
Identified Species:
27.88
UniProt:
Q86VQ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VQ0
NP_001116241.1
697
80554
Y441
P
E
W
E
T
G
R
Y
Q
L
G
M
Y
P
I
Chimpanzee
Pan troglodytes
XP_527439
697
80636
Y441
P
E
W
E
T
G
R
Y
Q
L
G
M
Y
P
I
Rhesus Macaque
Macaca mulatta
XP_001113835
697
80763
Y441
P
E
G
E
A
G
K
Y
Q
L
E
I
Y
Q
I
Dog
Lupus familis
XP_539014
700
80916
Y444
P
T
L
E
T
G
R
Y
Q
M
E
M
Y
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80ST9
704
80143
F441
L
A
L
E
A
G
R
F
P
T
E
N
Y
Q
A
Rat
Rattus norvegicus
Q5U2Y9
727
82591
V442
L
V
L
E
A
G
S
V
Q
T
E
S
Y
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520366
909
100353
S679
A
D
P
E
T
D
P
S
E
R
G
R
Q
P
V
Chicken
Gallus gallus
XP_419870
683
79593
H447
T
K
M
E
T
E
T
H
K
P
E
I
E
T
E
Frog
Xenopus laevis
Q9PW73
1335
154049
V862
M
D
M
Q
K
T
Q
V
E
L
D
K
K
A
C
Zebra Danio
Brachydanio rerio
XP_001919911
754
87027
E475
T
E
L
L
K
D
V
E
R
Q
R
L
D
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730235
569
63849
S346
S
T
L
S
Q
V
L
S
A
Q
G
K
I
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788900
765
88095
D436
I
K
K
R
E
R
L
D
E
E
K
M
R
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.2
83.4
N.A.
69.5
67.4
N.A.
35.8
47.4
20.3
33.2
N.A.
21.2
N.A.
N.A.
23.2
Protein Similarity:
100
99.1
96.8
89.8
N.A.
81.9
78.2
N.A.
50.3
64.8
33.4
53.4
N.A.
40
N.A.
N.A.
41.7
P-Site Identity:
100
100
60
66.6
N.A.
26.6
26.6
N.A.
26.6
13.3
6.6
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
73.3
73.3
N.A.
33.3
26.6
N.A.
46.6
40
33.3
20
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
25
0
0
0
9
0
0
0
0
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
17
0
0
0
17
0
9
0
0
9
0
9
0
9
% D
% Glu:
0
34
0
67
9
9
0
9
25
9
42
0
9
0
17
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
50
0
0
0
0
34
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
17
9
0
34
% I
% Lys:
0
17
9
0
17
0
9
0
9
0
9
17
9
0
0
% K
% Leu:
17
0
42
9
0
0
17
0
0
34
0
9
0
0
0
% L
% Met:
9
0
17
0
0
0
0
0
0
9
0
34
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
34
0
9
0
0
0
9
0
9
9
0
0
0
25
0
% P
% Gln:
0
0
0
9
9
0
9
0
42
17
0
0
9
42
0
% Q
% Arg:
0
0
0
9
0
9
34
0
9
9
9
9
9
0
0
% R
% Ser:
9
0
0
9
0
0
9
17
0
0
0
9
0
17
0
% S
% Thr:
17
17
0
0
42
9
9
0
0
17
0
0
0
9
0
% T
% Val:
0
9
0
0
0
9
9
17
0
0
0
0
0
0
17
% V
% Trp:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _