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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCA5
All Species:
10
Human Site:
Y486
Identified Species:
20
UniProt:
Q86VQ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VQ0
NP_001116241.1
697
80554
Y486
Q
D
S
R
N
L
K
Y
P
V
L
P
L
L
P
Chimpanzee
Pan troglodytes
XP_527439
697
80636
Y486
Q
D
S
R
N
L
K
Y
P
V
L
P
L
L
P
Rhesus Macaque
Macaca mulatta
XP_001113835
697
80763
Y486
Q
D
S
R
N
L
K
Y
P
V
L
P
L
L
P
Dog
Lupus familis
XP_539014
700
80916
C489
Q
D
S
R
N
T
K
C
P
P
L
P
L
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80ST9
704
80143
L491
G
R
A
P
L
P
L
L
P
N
F
E
S
K
L
Rat
Rattus norvegicus
Q5U2Y9
727
82591
R486
Q
D
P
Q
S
L
S
R
P
L
L
P
L
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520366
909
100353
D705
L
A
K
L
K
E
I
D
R
E
I
R
N
P
L
Chicken
Gallus gallus
XP_419870
683
79593
Q480
N
E
I
D
R
E
T
Q
N
V
M
N
M
K
L
Frog
Xenopus laevis
Q9PW73
1335
154049
L952
E
E
R
D
H
E
V
L
D
M
D
Q
L
L
K
Zebra Danio
Brachydanio rerio
XP_001919911
754
87027
S508
E
D
R
R
I
G
M
S
V
S
Q
K
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730235
569
63849
E371
A
V
A
V
P
K
M
E
S
V
Q
V
S
K
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788900
765
88095
E461
Q
R
K
R
Q
A
D
E
E
E
W
R
R
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.2
83.4
N.A.
69.5
67.4
N.A.
35.8
47.4
20.3
33.2
N.A.
21.2
N.A.
N.A.
23.2
Protein Similarity:
100
99.1
96.8
89.8
N.A.
81.9
78.2
N.A.
50.3
64.8
33.4
53.4
N.A.
40
N.A.
N.A.
41.7
P-Site Identity:
100
100
100
80
N.A.
6.6
60
N.A.
0
6.6
13.3
13.3
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
80
N.A.
13.3
80
N.A.
6.6
26.6
40
20
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
0
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
50
0
17
0
0
9
9
9
0
9
0
0
0
0
% D
% Glu:
17
17
0
0
0
25
0
17
9
17
0
9
9
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
9
0
9
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
17
0
9
9
34
0
0
0
0
9
0
25
9
% K
% Leu:
9
0
0
9
9
34
9
17
0
9
42
0
50
50
34
% L
% Met:
0
0
0
0
0
0
17
0
0
9
9
0
9
0
0
% M
% Asn:
9
0
0
0
34
0
0
0
9
9
0
9
9
0
0
% N
% Pro:
0
0
9
9
9
9
0
0
50
9
0
42
0
17
42
% P
% Gln:
50
0
0
9
9
0
0
9
0
0
17
9
0
0
0
% Q
% Arg:
0
17
17
50
9
0
0
9
9
0
0
17
9
0
9
% R
% Ser:
0
0
34
0
9
0
9
9
9
9
0
0
17
0
0
% S
% Thr:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% T
% Val:
0
9
0
9
0
0
9
0
9
42
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _