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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM134C All Species: 22.73
Human Site: S285 Identified Species: 50
UniProt: Q86VR2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VR2 NP_835227.1 466 51396 S285 R E L A I T D S E H S D A E V
Chimpanzee Pan troglodytes XP_001162621 466 51406 S285 R E L A I T D S E H S D A E V
Rhesus Macaque Macaca mulatta XP_001110850 466 51367 S285 R E L A I T D S E H S D A E V
Dog Lupus familis XP_548087 369 40751 D192 I T D S E H S D A E V S C T D
Cat Felis silvestris
Mouse Mus musculus Q9CQV4 466 51619 S285 R E L A I T D S E H S D A E V
Rat Rattus norvegicus Q5FVM3 480 52763 T289 K E L S V S D T D V S E V S W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508730 288 30789 A111 E R Q L R R P A L H P E H A L
Chicken Gallus gallus XP_001234118 435 48761 L257 D S V V A K E L T I S D S E H
Frog Xenopus laevis NP_001089401 339 37757 E162 E L C H Y L S E C W I T Y Q Q
Zebra Danio Brachydanio rerio XP_694371 500 54283 S286 K E L A L T D S E H S D A E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789536 515 56860 S257 R V I G A T P S S S C L G T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.5 74.2 N.A. 91.1 35 N.A. 40.5 66.3 29.6 51 N.A. N.A. N.A. N.A. 21.7
Protein Similarity: 100 99.7 99.1 77 N.A. 94.4 52 N.A. 47.8 76.8 44.2 66.4 N.A. N.A. N.A. N.A. 36.5
P-Site Identity: 100 100 100 0 N.A. 100 26.6 N.A. 6.6 20 0 80 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 6.6 N.A. 100 73.3 N.A. 26.6 40 6.6 100 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 46 19 0 0 10 10 0 0 0 46 10 0 % A
% Cys: 0 0 10 0 0 0 0 0 10 0 10 0 10 0 0 % C
% Asp: 10 0 10 0 0 0 55 10 10 0 0 55 0 0 10 % D
% Glu: 19 55 0 0 10 0 10 10 46 10 0 19 0 55 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 10 0 10 0 0 0 55 0 0 10 0 10 % H
% Ile: 10 0 10 0 37 0 0 0 0 10 10 0 0 0 10 % I
% Lys: 19 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 55 10 10 10 0 10 10 0 0 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 19 0 0 0 10 0 0 0 10 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 10 % Q
% Arg: 46 10 0 0 10 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 19 0 10 19 55 10 10 64 10 10 10 0 % S
% Thr: 0 10 0 0 0 55 0 10 10 0 0 10 0 19 0 % T
% Val: 0 10 10 10 10 0 0 0 0 10 10 0 10 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _