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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM134C
All Species:
17.27
Human Site:
S435
Identified Species:
38
UniProt:
Q86VR2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VR2
NP_835227.1
466
51396
S435
R
G
F
L
R
S
P
S
S
D
L
D
T
D
A
Chimpanzee
Pan troglodytes
XP_001162621
466
51406
S435
R
G
F
L
R
S
P
S
S
D
L
D
T
D
A
Rhesus Macaque
Macaca mulatta
XP_001110850
466
51367
S435
R
G
F
L
R
S
P
S
S
D
L
D
T
D
A
Dog
Lupus familis
XP_548087
369
40751
S339
G
F
L
R
A
P
S
S
D
L
D
T
D
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQV4
466
51619
S435
R
G
F
L
R
A
P
S
S
D
L
D
T
D
A
Rat
Rattus norvegicus
Q5FVM3
480
52763
D437
T
D
T
E
E
G
D
D
F
E
L
L
D
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508730
288
30789
G258
L
L
Q
A
L
P
A
G
T
T
L
P
G
H
L
Chicken
Gallus gallus
XP_001234118
435
48761
S404
K
T
Y
L
R
T
A
S
L
D
L
D
T
D
V
Frog
Xenopus laevis
NP_001089401
339
37757
E309
D
S
E
L
S
D
E
E
A
S
I
L
E
S
G
Zebra Danio
Brachydanio rerio
XP_694371
500
54283
R441
P
R
A
G
A
A
P
R
G
F
R
K
Q
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789536
515
56860
P419
S
L
A
G
L
S
D
P
T
A
A
T
S
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.5
74.2
N.A.
91.1
35
N.A.
40.5
66.3
29.6
51
N.A.
N.A.
N.A.
N.A.
21.7
Protein Similarity:
100
99.7
99.1
77
N.A.
94.4
52
N.A.
47.8
76.8
44.2
66.4
N.A.
N.A.
N.A.
N.A.
36.5
P-Site Identity:
100
100
100
6.6
N.A.
93.3
13.3
N.A.
6.6
53.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
100
20
N.A.
13.3
73.3
20
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
10
19
19
19
0
10
10
10
0
0
10
46
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
10
19
10
10
46
10
46
19
46
0
% D
% Glu:
0
0
10
10
10
0
10
10
0
10
0
0
10
10
10
% E
% Phe:
0
10
37
0
0
0
0
0
10
10
0
0
0
0
0
% F
% Gly:
10
37
0
19
0
10
0
10
10
0
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% K
% Leu:
10
19
10
55
19
0
0
0
10
10
64
19
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
19
46
10
0
0
0
10
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% Q
% Arg:
37
10
0
10
46
0
0
10
0
0
10
0
0
0
0
% R
% Ser:
10
10
0
0
10
37
10
55
37
10
0
0
10
19
10
% S
% Thr:
10
10
10
0
0
10
0
0
19
10
0
19
46
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _