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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM134C
All Species:
15.45
Human Site:
T427
Identified Species:
34
UniProt:
Q86VR2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VR2
NP_835227.1
466
51396
T427
G
A
P
A
Q
R
A
T
R
G
F
L
R
S
P
Chimpanzee
Pan troglodytes
XP_001162621
466
51406
T427
G
A
P
A
Q
R
A
T
R
G
F
L
R
S
P
Rhesus Macaque
Macaca mulatta
XP_001110850
466
51367
T427
G
A
P
A
Q
R
A
T
R
G
F
L
R
S
P
Dog
Lupus familis
XP_548087
369
40751
R331
P
P
P
R
R
A
T
R
G
F
L
R
A
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQV4
466
51619
T427
G
P
P
P
R
R
A
T
R
G
F
L
R
A
P
Rat
Rattus norvegicus
Q5FVM3
480
52763
D429
A
A
P
T
P
G
D
D
T
D
T
E
E
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508730
288
30789
L250
G
E
A
T
L
P
E
L
L
L
Q
A
L
P
A
Chicken
Gallus gallus
XP_001234118
435
48761
A396
S
D
N
L
H
R
D
A
K
T
Y
L
R
T
A
Frog
Xenopus laevis
NP_001089401
339
37757
T301
T
A
L
A
L
S
I
T
D
S
E
L
S
D
E
Zebra Danio
Brachydanio rerio
XP_694371
500
54283
G433
Q
G
P
R
R
E
S
G
P
R
A
G
A
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789536
515
56860
T411
A
V
M
S
E
A
V
T
S
L
A
G
L
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.5
74.2
N.A.
91.1
35
N.A.
40.5
66.3
29.6
51
N.A.
N.A.
N.A.
N.A.
21.7
Protein Similarity:
100
99.7
99.1
77
N.A.
94.4
52
N.A.
47.8
76.8
44.2
66.4
N.A.
N.A.
N.A.
N.A.
36.5
P-Site Identity:
100
100
100
6.6
N.A.
73.3
13.3
N.A.
6.6
20
26.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
86.6
13.3
N.A.
6.6
40
26.6
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
46
10
37
0
19
37
10
0
0
19
10
19
19
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
19
10
10
10
0
0
0
10
19
% D
% Glu:
0
10
0
0
10
10
10
0
0
0
10
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
37
0
0
0
0
% F
% Gly:
46
10
0
0
0
10
0
10
10
37
0
19
0
10
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
19
0
0
10
10
19
10
55
19
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
19
64
10
10
10
0
0
10
0
0
0
0
19
46
% P
% Gln:
10
0
0
0
28
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
19
28
46
0
10
37
10
0
10
46
0
0
% R
% Ser:
10
0
0
10
0
10
10
0
10
10
0
0
10
37
10
% S
% Thr:
10
0
0
19
0
0
10
55
10
10
10
0
0
10
0
% T
% Val:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _