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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM134C All Species: 21.82
Human Site: Y216 Identified Species: 48
UniProt: Q86VR2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VR2 NP_835227.1 466 51396 Y216 H R L W D R A Y V R L K P A L
Chimpanzee Pan troglodytes XP_001162621 466 51406 Y216 H R L W D R A Y V R L K P A L
Rhesus Macaque Macaca mulatta XP_001110850 466 51367 Y216 H R L W D R A Y V R L K P A L
Dog Lupus familis XP_548087 369 40751 D130 K P A L Q R L D F S V R G Y M
Cat Felis silvestris
Mouse Mus musculus Q9CQV4 466 51619 Y216 H R L W D R A Y V R L K P V L
Rat Rattus norvegicus Q5FVM3 480 52763 Y226 N D I G Q K I Y S K V K S I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508730 288 30789 R49 A G A G G A S R S W A G P A Y
Chicken Gallus gallus XP_001234118 435 48761 Y194 H R L G H R M Y M K L E P A L
Frog Xenopus laevis NP_001089401 339 37757 V100 S Y L S P R P V F L L C F F M
Zebra Danio Brachydanio rerio XP_694371 500 54283 C218 Y R L W Q R V C V K L E P A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789536 515 56860 Y184 H D V S G K I Y T K L H P F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.5 74.2 N.A. 91.1 35 N.A. 40.5 66.3 29.6 51 N.A. N.A. N.A. N.A. 21.7
Protein Similarity: 100 99.7 99.1 77 N.A. 94.4 52 N.A. 47.8 76.8 44.2 66.4 N.A. N.A. N.A. N.A. 36.5
P-Site Identity: 100 100 100 6.6 N.A. 93.3 20 N.A. 13.3 60 20 60 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 100 26.6 N.A. 93.3 53.3 N.A. 20 80 26.6 80 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 19 0 0 10 37 0 0 0 10 0 0 55 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % C
% Asp: 0 19 0 0 37 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 19 0 0 0 10 19 0 % F
% Gly: 0 10 0 28 19 0 0 0 0 0 0 10 10 0 0 % G
% His: 55 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 10 0 0 0 19 0 0 0 0 0 0 10 0 % I
% Lys: 10 0 0 0 0 19 0 0 0 37 0 46 0 0 0 % K
% Leu: 0 0 64 10 0 0 10 0 0 10 73 0 0 0 73 % L
% Met: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 19 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 10 0 10 0 0 0 0 0 73 0 0 % P
% Gln: 0 0 0 0 28 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 55 0 0 0 73 0 10 0 37 0 10 0 0 0 % R
% Ser: 10 0 0 19 0 0 10 0 19 10 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 10 10 46 0 19 0 0 10 0 % V
% Trp: 0 0 0 46 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 10 10 0 0 0 0 0 64 0 0 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _