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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IQCH All Species: 0.91
Human Site: S121 Identified Species: 4
UniProt: Q86VS3 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VS3 NP_001026885.1 1027 117349 S121 P Q R Q H S S S L P V F P R A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544740 1029 117533 F121 T Q R Q H G T F P H A F P K I
Cat Felis silvestris
Mouse Mus musculus Q9D2K4 1071 122572 P157 A S Y G I S L P H I N Q R K A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516145 1067 120557 V134 L S P S L P S V L L L F P R S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LXZ7 1059 118950 T121 S P G E K H K T A F I M R L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798652 1007 113280 A121 E R G L I P P A A E L T L D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 81.6 N.A. 70.6 N.A. N.A. 60.6 N.A. N.A. 41.4 N.A. N.A. N.A. N.A. 44.4
Protein Similarity: 100 N.A. N.A. 90.4 N.A. 82.2 N.A. N.A. 74.8 N.A. N.A. 59.2 N.A. N.A. N.A. N.A. 61.1
P-Site Identity: 100 N.A. N.A. 40 N.A. 13.3 N.A. N.A. 33.3 N.A. N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 N.A. N.A. 53.3 N.A. 20 N.A. N.A. 46.6 N.A. N.A. 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 0 0 17 34 0 17 0 0 0 34 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % D
% Glu: 17 0 0 17 0 0 0 0 0 17 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 17 0 17 0 50 0 0 0 % F
% Gly: 0 0 34 17 0 17 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 34 17 0 0 17 17 0 0 0 0 0 % H
% Ile: 0 0 0 0 34 0 0 0 0 17 17 0 0 0 17 % I
% Lys: 0 0 0 0 17 0 17 0 0 0 0 0 0 34 0 % K
% Leu: 17 0 0 17 17 0 17 0 34 17 34 0 17 17 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % N
% Pro: 17 17 17 0 0 34 17 17 17 17 0 0 50 0 17 % P
% Gln: 0 34 0 34 0 0 0 0 0 0 0 17 0 0 0 % Q
% Arg: 0 17 34 0 0 0 0 0 0 0 0 0 34 34 0 % R
% Ser: 17 34 0 17 0 34 34 17 0 0 0 0 0 0 17 % S
% Thr: 17 0 0 0 0 0 17 17 0 0 0 17 0 0 0 % T
% Val: 0 0 0 0 0 0 0 17 0 0 17 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _