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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOOK3
All Species:
23.03
Human Site:
S15
Identified Species:
42.22
UniProt:
Q86VS8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VS8
NP_115786.1
718
83126
S15
E
R
A
E
L
C
E
S
L
L
T
W
I
Q
T
Chimpanzee
Pan troglodytes
XP_001145184
717
83050
S15
E
R
A
E
L
C
E
S
L
L
T
W
I
Q
T
Rhesus Macaque
Macaca mulatta
XP_001099564
718
83173
S15
E
R
A
E
L
C
E
S
L
L
T
W
I
Q
T
Dog
Lupus familis
XP_532787
718
83205
S15
E
R
V
E
L
C
E
S
L
L
T
W
I
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUK6
718
83199
S15
E
R
V
E
L
C
E
S
L
L
T
W
I
Q
T
Rat
Rattus norvegicus
NP_001129570
718
83162
S15
E
R
V
E
L
C
E
S
L
L
T
W
I
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509642
837
96168
I134
M
S
T
A
S
I
Q
I
V
V
F
T
I
Q
T
Chicken
Gallus gallus
Q5ZJ27
718
82961
W17
L
C
D
S
L
I
L
W
L
Q
T
F
N
T
A
Frog
Xenopus laevis
Q6GQ73
719
83201
T15
D
L
C
E
S
L
L
T
W
I
Q
T
F
H
V
Zebra Danio
Brachydanio rerio
Q5TZ80
715
83097
W15
L
C
E
S
L
I
I
W
L
Q
T
F
K
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24185
679
76646
W15
M
Y
Y
S
L
L
E
W
F
K
T
L
N
L
N
Honey Bee
Apis mellifera
XP_395724
701
81483
D17
I
K
W
L
D
T
F
D
L
Q
S
S
H
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796541
586
67269
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98
98.8
N.A.
97.7
97.9
N.A.
82.8
58.5
89.5
58.2
N.A.
35.9
43.7
N.A.
46.6
Protein Similarity:
100
99
98.6
99.8
N.A.
99.1
99.4
N.A.
85.1
76
95.9
77.3
N.A.
58
67.5
N.A.
61.9
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
20
20
6.6
20
N.A.
20
13.3
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
40
26.6
26.6
26.6
N.A.
20
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
8
0
0
0
0
0
0
0
0
0
0
16
% A
% Cys:
0
16
8
0
0
47
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
47
0
8
54
0
0
54
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
8
0
8
16
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
8
0
0
0
0
24
8
8
0
8
0
0
54
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
16
8
0
8
70
16
16
0
70
47
0
8
0
8
0
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
24
8
0
0
54
0
% Q
% Arg:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
24
16
0
0
47
0
0
8
8
0
8
0
% S
% Thr:
0
0
8
0
0
8
0
8
0
0
70
16
0
16
62
% T
% Val:
0
0
24
0
0
0
0
0
8
8
0
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
24
8
0
0
47
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _