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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HOOK3 All Species: 34.85
Human Site: S704 Identified Species: 63.89
UniProt: Q86VS8 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VS8 NP_115786.1 718 83126 S704 R Q R Q A T S S R R S Y P G H
Chimpanzee Pan troglodytes XP_001145184 717 83050 S703 R Q R Q A T S S R R S Y P G H
Rhesus Macaque Macaca mulatta XP_001099564 718 83173 S704 R Q R Q A T S S R R S Y P G H
Dog Lupus familis XP_532787 718 83205 T704 R Q R Q A T S T R R S Y P G H
Cat Felis silvestris
Mouse Mus musculus Q8BUK6 718 83199 T704 R Q R Q A T S T R R S Y P G H
Rat Rattus norvegicus NP_001129570 718 83162 T704 R Q R Q A T S T R R S Y P G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509642 837 96168 T823 R Q R Q A T S T R R S Y P G H
Chicken Gallus gallus Q5ZJ27 718 82961 T704 Q Q R H V T N T R R N L P V K
Frog Xenopus laevis Q6GQ73 719 83201 S701 R Q R Q A T S S R R S Y P G H
Zebra Danio Brachydanio rerio Q5TZ80 715 83097 A701 Q Q R Q V T N A R R T M S I N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24185 679 76646 Q666 T F L A R Q R Q S A P R K S L
Honey Bee Apis mellifera XP_395724 701 81483 A685 G Q G Q S F L A R Q R Q P S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796541 586 67269 R573 Q R Q A S S R R S Q A I L N N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 98 98.8 N.A. 97.7 97.9 N.A. 82.8 58.5 89.5 58.2 N.A. 35.9 43.7 N.A. 46.6
Protein Similarity: 100 99 98.6 99.8 N.A. 99.1 99.4 N.A. 85.1 76 95.9 77.3 N.A. 58 67.5 N.A. 61.9
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 93.3 40 100 40 N.A. 0 26.6 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 66.6 100 73.3 N.A. 0 46.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 62 0 0 16 0 8 8 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 0 0 0 0 0 0 0 0 0 62 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 62 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % K
% Leu: 0 0 8 0 0 0 8 0 0 0 0 8 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 16 0 0 0 8 0 0 8 16 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 77 0 0 % P
% Gln: 24 85 8 77 0 8 0 8 0 16 0 8 0 0 0 % Q
% Arg: 62 8 77 0 8 0 16 8 85 77 8 8 0 0 0 % R
% Ser: 0 0 0 0 16 8 62 31 16 0 62 0 8 16 0 % S
% Thr: 8 0 0 0 0 77 0 39 0 0 8 0 0 0 0 % T
% Val: 0 0 0 0 16 0 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 62 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _