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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOOK3
All Species:
43.94
Human Site:
Y268
Identified Species:
80.56
UniProt:
Q86VS8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VS8
NP_115786.1
718
83126
Y268
L
E
A
A
K
D
D
Y
R
I
R
C
E
E
L
Chimpanzee
Pan troglodytes
XP_001145184
717
83050
Y268
L
E
A
A
K
D
D
Y
R
I
R
C
E
E
L
Rhesus Macaque
Macaca mulatta
XP_001099564
718
83173
Y268
L
E
A
A
K
D
D
Y
R
I
R
C
E
E
L
Dog
Lupus familis
XP_532787
718
83205
Y268
L
E
A
A
K
D
D
Y
R
I
R
C
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUK6
718
83199
Y268
L
E
A
A
K
D
D
Y
R
I
R
C
E
E
L
Rat
Rattus norvegicus
NP_001129570
718
83162
Y268
L
E
A
A
K
D
D
Y
R
I
R
C
E
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509642
837
96168
Y387
L
E
A
A
K
D
D
Y
R
I
R
C
E
E
L
Chicken
Gallus gallus
Q5ZJ27
718
82961
Y267
L
E
A
A
K
D
D
Y
R
V
H
C
E
D
L
Frog
Xenopus laevis
Q6GQ73
719
83201
Y265
L
E
A
S
K
D
D
Y
R
I
R
C
E
E
L
Zebra Danio
Brachydanio rerio
Q5TZ80
715
83097
Y264
L
E
A
A
K
D
D
Y
R
I
H
C
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24185
679
76646
L275
S
E
G
A
R
E
D
L
K
I
K
A
Q
Q
Q
Honey Bee
Apis mellifera
XP_395724
701
81483
Y264
V
E
T
S
R
D
D
Y
R
L
K
I
E
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796541
586
67269
D199
T
L
K
K
K
L
E
D
L
G
D
L
K
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98
98.8
N.A.
97.7
97.9
N.A.
82.8
58.5
89.5
58.2
N.A.
35.9
43.7
N.A.
46.6
Protein Similarity:
100
99
98.6
99.8
N.A.
99.1
99.4
N.A.
85.1
76
95.9
77.3
N.A.
58
67.5
N.A.
61.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
80
93.3
93.3
N.A.
26.6
46.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
100
93.3
N.A.
66.6
80
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
77
77
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
77
0
0
0
% C
% Asp:
0
0
0
0
0
85
93
8
0
0
8
0
0
8
0
% D
% Glu:
0
93
0
0
0
8
8
0
0
0
0
0
85
70
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
77
0
8
0
0
0
% I
% Lys:
0
0
8
8
85
0
0
0
8
0
16
0
8
0
0
% K
% Leu:
77
8
0
0
0
8
0
8
8
8
0
8
0
8
85
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
16
% Q
% Arg:
0
0
0
0
16
0
0
0
85
0
62
0
0
8
0
% R
% Ser:
8
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _