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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COMTD1 All Species: 13.33
Human Site: S60 Identified Species: 26.67
UniProt: Q86VU5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VU5 NP_653190.2 262 28809 S60 R L W Q Y L L S R S M R E H P
Chimpanzee Pan troglodytes P86243 291 32105 V61 R H Y F R L L V R T V L L R S
Rhesus Macaque Macaca mulatta B6CZ46 296 32648 H94 A F S Y V L T H A L P G D P G
Dog Lupus familis XP_546175 434 46321 S232 P L W R Y L L S R S M R E H P
Cat Felis silvestris
Mouse Mus musculus Q8BIG7 262 28942 S60 P L W Q Y L L S R S M R E H P
Rat Rattus norvegicus B6CZ62 258 28845 H56 A F S Y V I T H A L P G D P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506779 263 29416 S61 P L W S Y V L S H S L R E H P
Chicken Gallus gallus XP_421605 347 38509 D145 P L W Q Y I L D H S L R E H P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001157280 238 26369 A56 R L R T M E D A R N V M M V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa O65922 247 27935 M61 A K H P W N I M T T S A D E G
Maize Zea mays Q9XGD5 264 29333 S54 Y Q Y I L D T S V Y P R E P E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49499 259 29137 M58 Y P R E P E S M K E L R E V T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.7 24.6 53.4 N.A. 85.5 23.6 N.A. 58.9 41.5 N.A. 44.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 38.8 37.8 55.7 N.A. 92.3 38.9 N.A. 73.3 56.7 N.A. 65.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 6.6 86.6 N.A. 93.3 0 N.A. 66.6 66.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 46.6 13.3 93.3 N.A. 93.3 13.3 N.A. 80 80 N.A. 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 34.3 37.8 N.A. 33.5 N.A. N.A.
Protein Similarity: 54.2 54.1 N.A. 54.2 N.A. N.A.
P-Site Identity: 0 20 N.A. 13.3 N.A. N.A.
P-Site Similarity: 26.6 26.6 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 0 0 0 0 0 9 17 0 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 9 9 0 0 0 0 25 0 0 % D
% Glu: 0 0 0 9 0 17 0 0 0 9 0 0 59 9 9 % E
% Phe: 0 17 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 25 % G
% His: 0 9 9 0 0 0 0 17 17 0 0 0 0 42 0 % H
% Ile: 0 0 0 9 0 17 9 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % K
% Leu: 0 50 0 0 9 42 50 0 0 17 25 9 9 0 0 % L
% Met: 0 0 0 0 9 0 0 17 0 0 25 9 9 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 0 % N
% Pro: 34 9 0 9 9 0 0 0 0 0 25 0 0 25 42 % P
% Gln: 0 9 0 25 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 25 0 17 9 9 0 0 0 42 0 0 59 0 9 0 % R
% Ser: 0 0 17 9 0 0 9 42 0 42 9 0 0 0 9 % S
% Thr: 0 0 0 9 0 0 25 0 9 17 0 0 0 0 9 % T
% Val: 0 0 0 0 17 9 0 9 9 0 17 0 0 17 0 % V
% Trp: 0 0 42 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 17 0 17 17 42 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _