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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COMTD1
All Species:
14.85
Human Site:
Y57
Identified Species:
29.7
UniProt:
Q86VU5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VU5
NP_653190.2
262
28809
Y57
E
D
S
R
L
W
Q
Y
L
L
S
R
S
M
R
Chimpanzee
Pan troglodytes
P86243
291
32105
R58
V
R
Y
R
H
Y
F
R
L
L
V
R
T
V
L
Rhesus Macaque
Macaca mulatta
B6CZ46
296
32648
V91
E
E
R
A
F
S
Y
V
L
T
H
A
L
P
G
Dog
Lupus familis
XP_546175
434
46321
Y229
E
D
S
P
L
W
R
Y
L
L
S
R
S
M
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIG7
262
28942
Y57
E
D
N
P
L
W
Q
Y
L
L
S
R
S
M
R
Rat
Rattus norvegicus
B6CZ62
258
28845
V53
E
E
R
A
F
S
Y
V
I
T
H
A
L
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506779
263
29416
Y58
R
K
S
P
L
W
S
Y
V
L
S
H
S
L
R
Chicken
Gallus gallus
XP_421605
347
38509
Y142
K
S
S
P
L
W
Q
Y
I
L
D
H
S
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001157280
238
26369
M53
T
K
L
R
L
R
T
M
E
D
A
R
N
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
O65922
247
27935
W58
E
L
T
A
K
H
P
W
N
I
M
T
T
S
A
Maize
Zea mays
Q9XGD5
264
29333
L51
D
D
L
Y
Q
Y
I
L
D
T
S
V
Y
P
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49499
259
29137
P55
T
S
V
Y
P
R
E
P
E
S
M
K
E
L
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.7
24.6
53.4
N.A.
85.5
23.6
N.A.
58.9
41.5
N.A.
44.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
38.8
37.8
55.7
N.A.
92.3
38.9
N.A.
73.3
56.7
N.A.
65.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
13.3
86.6
N.A.
86.6
6.6
N.A.
53.3
53.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
20
93.3
N.A.
93.3
20
N.A.
66.6
73.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
34.3
37.8
N.A.
33.5
N.A.
N.A.
Protein Similarity:
54.2
54.1
N.A.
54.2
N.A.
N.A.
P-Site Identity:
6.6
20
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
33.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
25
0
0
0
0
0
0
9
17
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
34
0
0
0
0
0
0
9
9
9
0
0
0
0
% D
% Glu:
50
17
0
0
0
0
9
0
17
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
17
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% G
% His:
0
0
0
0
9
9
0
0
0
0
17
17
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
17
9
0
0
0
0
0
% I
% Lys:
9
17
0
0
9
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
9
17
0
50
0
0
9
42
50
0
0
17
25
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
17
0
0
25
9
% M
% Asn:
0
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
0
0
0
34
9
0
9
9
0
0
0
0
0
25
0
% P
% Gln:
0
0
0
0
9
0
25
0
0
0
0
0
0
0
0
% Q
% Arg:
9
9
17
25
0
17
9
9
0
0
0
42
0
0
59
% R
% Ser:
0
17
34
0
0
17
9
0
0
9
42
0
42
9
0
% S
% Thr:
17
0
9
0
0
0
9
0
0
25
0
9
17
0
0
% T
% Val:
9
0
9
0
0
0
0
17
9
0
9
9
0
17
0
% V
% Trp:
0
0
0
0
0
42
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
17
0
17
17
42
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _