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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MON1A All Species: 43.64
Human Site: Y450 Identified Species: 68.57
UniProt: Q86VX9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VX9 NP_001135973.1 555 62131 Y450 P D L R H F L Y K S K S S G L
Chimpanzee Pan troglodytes XP_516471 555 62113 Y450 P D L R H F L Y K S K S S G L
Rhesus Macaque Macaca mulatta XP_001092852 460 50936 E360 S S S S S F R E G E A W T P V
Dog Lupus familis XP_850897 578 64592 Y473 P D L R H F L Y K S K S S G L
Cat Felis silvestris
Mouse Mus musculus Q6PDG8 556 62113 Y451 P D L R H F L Y K S K S S G L
Rat Rattus norvegicus NP_001119756 527 59098 Y422 P D L R H F L Y K S K S S G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508437 766 86058 Y167 P E L R H F I Y K S K S S G L
Chicken Gallus gallus Q5ZIH2 549 62030 Y444 P D L R H F I Y K S K S S G L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001092240 525 59633 Y420 P E L R H F V Y K S K S S G L
Tiger Blowfish Takifugu rubipres Q9YGN1 520 58815 Y415 P E L R H F L Y K S K S S G L
Fruit Fly Dros. melanogaster NP_608868 528 59816 Y423 P E L R H F L Y K P K S T A Q
Honey Bee Apis mellifera XP_396160 493 56303 T393 V L Y K C R S T A Q F W S P G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784800 511 57914 A412 L Y K S R S T A Q Y T A P E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53129 644 73475 Y493 P M V H H F I Y K S K Q N V Q
Red Bread Mold Neurospora crassa Q870Q4 678 73710 P573 P A F E T S S P P L P S S S P
Conservation
Percent
Protein Identity: 100 100 80.9 93 N.A. 94.2 89.9 N.A. 60.5 78.3 N.A. 60 61.6 38.3 40.9 N.A. 33.5
Protein Similarity: 100 100 81.4 93.5 N.A. 95.8 92.2 N.A. 66.5 86.3 N.A. 76.5 74.5 58.2 61.6 N.A. 52.2
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 86.6 93.3 N.A. 86.6 93.3 66.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 100 100 N.A. 100 100 80 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.9 27.4
Protein Similarity: N.A. N.A. N.A. N.A. 44.4 44.8
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 20
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 7 7 0 7 7 0 7 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 27 0 7 0 0 0 7 0 7 0 0 0 7 0 % E
% Phe: 0 0 7 0 0 80 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 7 0 0 0 0 60 7 % G
% His: 0 0 0 7 74 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 7 0 0 0 0 74 0 74 0 0 0 0 % K
% Leu: 7 7 67 0 0 0 47 0 0 7 0 0 0 0 67 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % N
% Pro: 80 0 0 0 0 0 0 7 7 7 7 0 7 14 7 % P
% Gln: 0 0 0 0 0 0 0 0 7 7 0 7 0 0 14 % Q
% Arg: 0 0 0 67 7 7 7 0 0 0 0 0 0 0 0 % R
% Ser: 7 7 7 14 7 14 14 0 0 67 0 74 74 7 0 % S
% Thr: 0 0 0 0 7 0 7 7 0 0 7 0 14 0 0 % T
% Val: 7 0 7 0 0 0 7 0 0 0 0 0 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 % W
% Tyr: 0 7 7 0 0 0 0 74 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _