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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM200A All Species: 8.48
Human Site: S335 Identified Species: 20.74
UniProt: Q86VY9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VY9 NP_443145.1 491 54356 S335 V V P L P N T S E S F Q P V S
Chimpanzee Pan troglodytes XP_001168480 491 54369 S335 V V P L P N T S E S F Q P V S
Rhesus Macaque Macaca mulatta XP_001104291 491 54443 S335 V A P L A D T S E S F Q P V S
Dog Lupus familis XP_855538 491 53947 G335 V L P P P N A G E P F Q P V G
Cat Felis silvestris
Mouse Mus musculus Q8C817 491 53989 G335 V V P L P S S G E S F Q P A V
Rat Rattus norvegicus NP_001102605 485 53450 G335 V V P L P S S G E P A S T L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512826 490 54235 N334 T V P V P D I N E S Y Q P A N
Chicken Gallus gallus XP_424670 489 54095 D335 A I P L T D T D E S C K P A M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5RGQ8 497 54951 K341 V P V P D I A K A F K P P G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_493076 400 44431 N255 I G Q H Q P I N D A G A K S L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.9 90.6 N.A. 90.6 89.8 N.A. 84.3 79.6 N.A. 63.7 N.A. N.A. N.A. 20.1 N.A.
Protein Similarity: 100 99.3 98.5 94.9 N.A. 96.1 95.3 N.A. 91.8 90.8 N.A. 77 N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: 100 100 80 60 N.A. 66.6 40 N.A. 46.6 40 N.A. 13.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 86.6 66.6 N.A. 80 60 N.A. 80 60 N.A. 13.3 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 10 0 20 0 10 10 10 10 0 30 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 10 30 0 10 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 80 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 50 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 30 0 0 10 0 0 10 10 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 10 20 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 10 10 10 0 0 % K
% Leu: 0 10 0 60 0 0 0 0 0 0 0 0 0 10 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 30 0 20 0 0 0 0 0 0 10 % N
% Pro: 0 10 80 20 60 10 0 0 0 20 0 10 80 0 0 % P
% Gln: 0 0 10 0 10 0 0 0 0 0 0 60 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 20 20 30 0 60 0 10 0 10 30 % S
% Thr: 10 0 0 0 10 0 40 0 0 0 0 0 10 0 0 % T
% Val: 70 50 10 10 0 0 0 0 0 0 0 0 0 40 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _