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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM200A
All Species:
8.48
Human Site:
S335
Identified Species:
20.74
UniProt:
Q86VY9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VY9
NP_443145.1
491
54356
S335
V
V
P
L
P
N
T
S
E
S
F
Q
P
V
S
Chimpanzee
Pan troglodytes
XP_001168480
491
54369
S335
V
V
P
L
P
N
T
S
E
S
F
Q
P
V
S
Rhesus Macaque
Macaca mulatta
XP_001104291
491
54443
S335
V
A
P
L
A
D
T
S
E
S
F
Q
P
V
S
Dog
Lupus familis
XP_855538
491
53947
G335
V
L
P
P
P
N
A
G
E
P
F
Q
P
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C817
491
53989
G335
V
V
P
L
P
S
S
G
E
S
F
Q
P
A
V
Rat
Rattus norvegicus
NP_001102605
485
53450
G335
V
V
P
L
P
S
S
G
E
P
A
S
T
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512826
490
54235
N334
T
V
P
V
P
D
I
N
E
S
Y
Q
P
A
N
Chicken
Gallus gallus
XP_424670
489
54095
D335
A
I
P
L
T
D
T
D
E
S
C
K
P
A
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RGQ8
497
54951
K341
V
P
V
P
D
I
A
K
A
F
K
P
P
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493076
400
44431
N255
I
G
Q
H
Q
P
I
N
D
A
G
A
K
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.9
90.6
N.A.
90.6
89.8
N.A.
84.3
79.6
N.A.
63.7
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
100
99.3
98.5
94.9
N.A.
96.1
95.3
N.A.
91.8
90.8
N.A.
77
N.A.
N.A.
N.A.
37.8
N.A.
P-Site Identity:
100
100
80
60
N.A.
66.6
40
N.A.
46.6
40
N.A.
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
86.6
66.6
N.A.
80
60
N.A.
80
60
N.A.
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
0
20
0
10
10
10
10
0
30
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
10
30
0
10
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
50
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
30
0
0
10
0
0
10
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
10
20
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
10
10
10
0
0
% K
% Leu:
0
10
0
60
0
0
0
0
0
0
0
0
0
10
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
30
0
20
0
0
0
0
0
0
10
% N
% Pro:
0
10
80
20
60
10
0
0
0
20
0
10
80
0
0
% P
% Gln:
0
0
10
0
10
0
0
0
0
0
0
60
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
20
20
30
0
60
0
10
0
10
30
% S
% Thr:
10
0
0
0
10
0
40
0
0
0
0
0
10
0
0
% T
% Val:
70
50
10
10
0
0
0
0
0
0
0
0
0
40
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _