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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RY8
All Species:
8.48
Human Site:
S263
Identified Species:
23.33
UniProt:
Q86VZ1
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VZ1
NP_835230.1
359
40635
S263
V
L
L
A
H
I
V
S
R
L
F
Y
G
K
S
Chimpanzee
Pan troglodytes
XP_001175457
367
41416
S271
V
L
L
A
H
I
V
S
R
L
F
Y
G
K
S
Rhesus Macaque
Macaca mulatta
XP_001115826
407
45478
G311
V
L
L
A
H
I
V
G
R
L
F
Y
G
K
S
Dog
Lupus familis
XP_548831
670
73379
S574
V
L
L
V
H
M
V
S
R
L
F
L
G
R
S
Cat
Felis silvestris
Mouse
Mus musculus
P55086
399
44734
P304
M
Y
F
I
C
F
A
P
S
N
L
L
L
V
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506392
355
40609
H259
N
N
F
V
L
L
A
H
M
V
N
R
L
F
F
Chicken
Gallus gallus
Q5ZI82
357
41225
V262
I
L
L
A
H
M
I
V
R
L
F
Y
E
G
S
Frog
Xenopus laevis
P47749
420
47417
K306
S
S
I
E
N
S
C
K
K
T
R
A
L
F
L
Zebra Danio
Brachydanio rerio
A5PLE7
368
41686
K267
D
L
L
Q
Y
M
I
K
K
L
R
Y
D
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
84
42.8
N.A.
32
N.A.
N.A.
62.6
60.4
29.5
26
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.2
85.7
46.4
N.A.
51.3
N.A.
N.A.
76
76.3
48.5
48.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
0
N.A.
N.A.
0
60
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
6.6
N.A.
N.A.
13.3
80
20
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
45
0
0
23
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% D
% Glu:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% E
% Phe:
0
0
23
0
0
12
0
0
0
0
56
0
0
23
12
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
0
0
45
12
0
% G
% His:
0
0
0
0
56
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
12
0
12
12
0
34
23
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
23
23
0
0
0
0
34
0
% K
% Leu:
0
67
67
0
12
12
0
0
0
67
12
23
34
0
12
% L
% Met:
12
0
0
0
0
34
0
0
12
0
0
0
0
0
0
% M
% Asn:
12
12
0
0
12
0
0
0
0
12
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
56
0
23
12
0
12
0
% R
% Ser:
12
12
0
0
0
12
0
34
12
0
0
0
0
0
56
% S
% Thr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% T
% Val:
45
0
0
23
0
0
45
12
0
12
0
0
0
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
12
0
0
0
0
0
0
56
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _