KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RY8
All Species:
18.48
Human Site:
Y294
Identified Species:
50.83
UniProt:
Q86VZ1
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VZ1
NP_835230.1
359
40635
Y294
C
L
D
P
F
V
Y
Y
F
A
S
R
E
F
Q
Chimpanzee
Pan troglodytes
XP_001175457
367
41416
Y302
C
L
D
P
F
V
Y
Y
F
A
S
R
E
F
Q
Rhesus Macaque
Macaca mulatta
XP_001115826
407
45478
Y342
C
L
D
P
F
V
Y
Y
F
A
S
R
E
F
Q
Dog
Lupus familis
XP_548831
670
73379
Y605
C
L
D
P
F
V
Y
Y
F
A
S
R
E
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
P55086
399
44734
S335
Y
L
V
A
L
C
L
S
T
L
N
S
C
I
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506392
355
40609
F290
L
N
N
C
L
D
P
F
I
Y
Y
F
A
S
K
Chicken
Gallus gallus
Q5ZI82
357
41225
Y293
C
I
D
P
F
I
Y
Y
F
A
S
K
E
F
Y
Frog
Xenopus laevis
P47749
420
47417
L337
V
L
F
L
T
H
Y
L
Q
E
A
N
E
F
L
Zebra Danio
Brachydanio rerio
A5PLE7
368
41686
L298
F
M
N
L
N
S
C
L
D
P
F
I
Y
F
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
84
42.8
N.A.
32
N.A.
N.A.
62.6
60.4
29.5
26
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.2
85.7
46.4
N.A.
51.3
N.A.
N.A.
76
76.3
48.5
48.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
N.A.
N.A.
0
73.3
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
13.3
N.A.
N.A.
20
93.3
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
0
56
12
0
12
0
0
% A
% Cys:
56
0
0
12
0
12
12
0
0
0
0
0
12
0
0
% C
% Asp:
0
0
56
0
0
12
0
0
12
0
0
0
0
0
12
% D
% Glu:
0
0
0
0
0
0
0
0
0
12
0
0
67
0
0
% E
% Phe:
12
0
12
0
56
0
0
12
56
0
12
12
0
78
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
12
0
0
12
0
0
12
0
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% K
% Leu:
12
67
0
23
23
0
12
23
0
12
0
0
0
0
12
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
23
0
12
0
0
0
0
0
12
12
0
0
0
% N
% Pro:
0
0
0
56
0
0
12
0
0
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
45
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
45
0
0
0
% R
% Ser:
0
0
0
0
0
12
0
12
0
0
56
12
0
12
0
% S
% Thr:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% T
% Val:
12
0
12
0
0
45
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
67
56
0
12
12
0
12
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _