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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR5B
All Species:
29.09
Human Site:
S45
Identified Species:
53.33
UniProt:
Q86VZ2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VZ2
NP_061942.2
330
36338
S45
V
G
H
T
E
A
V
S
S
V
K
F
S
P
N
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
T112
S
G
H
R
S
P
V
T
R
V
I
F
H
P
V
Rhesus Macaque
Macaca mulatta
XP_001112263
330
36273
S45
V
G
H
T
E
A
V
S
S
V
K
F
S
P
N
Dog
Lupus familis
XP_850117
334
36428
S49
A
G
H
T
K
A
V
S
S
V
K
F
S
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7H2
328
36014
S44
G
H
S
A
A
I
S
S
V
K
F
S
P
N
G
Rat
Rattus norvegicus
Q4V8C4
328
36030
S44
G
H
S
A
A
I
S
S
V
K
F
S
P
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506016
334
36605
S49
A
G
H
T
K
A
V
S
S
V
K
F
S
P
N
Chicken
Gallus gallus
Q9PTR5
410
46646
T112
S
G
H
R
S
P
V
T
R
V
I
F
H
P
V
Frog
Xenopus laevis
Q5FWQ6
415
45899
N97
A
H
I
L
P
L
T
N
V
A
F
N
K
S
G
Zebra Danio
Brachydanio rerio
Q803D2
410
46511
T112
S
G
H
R
S
P
V
T
R
V
I
F
H
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
S76
A
G
H
T
K
A
V
S
A
V
K
F
S
P
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
S91
E
G
H
T
K
S
I
S
S
A
K
F
S
P
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38123
315
34735
T31
D
G
Q
F
L
A
I
T
Q
G
L
N
I
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.5
97.5
82
N.A.
82.7
83.9
N.A.
85
28.7
23.8
27.7
N.A.
73.6
N.A.
56.9
N.A.
Protein Similarity:
100
46
99.6
88.9
N.A.
93
93.3
N.A.
90.4
46.8
41.2
45.6
N.A.
80.8
N.A.
71.2
N.A.
P-Site Identity:
100
40
100
86.6
N.A.
6.6
6.6
N.A.
86.6
40
0
40
N.A.
80
N.A.
60
N.A.
P-Site Similarity:
100
46.6
100
93.3
N.A.
6.6
6.6
N.A.
93.3
46.6
6.6
46.6
N.A.
93.3
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
0
16
16
47
0
0
8
16
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
24
70
0
0
0
% F
% Gly:
16
77
0
0
0
0
0
0
0
8
0
0
0
0
24
% G
% His:
0
24
70
0
0
0
0
0
0
0
0
0
24
0
0
% H
% Ile:
0
0
8
0
0
16
16
0
0
0
24
0
8
0
8
% I
% Lys:
0
0
0
0
31
0
0
0
0
16
47
0
8
0
0
% K
% Leu:
0
0
0
8
8
8
0
0
0
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
16
0
16
39
% N
% Pro:
0
0
0
0
8
24
0
0
0
0
0
0
16
70
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
24
0
0
0
0
24
0
0
0
0
0
0
% R
% Ser:
24
0
16
0
24
8
16
62
39
0
0
16
47
8
0
% S
% Thr:
0
0
0
47
0
0
8
31
0
0
0
0
0
0
0
% T
% Val:
16
0
0
0
0
0
62
0
24
62
0
0
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _